CAM7

Summary

Gene Symbol: CAM7
Description: calmodulin 7
Alias: AtCAM7, CALMODULIN 7, Z-box Binding Factor 3, ZBF3, calmodulin 7, calmodulin 7
Species: thale cress

Top Publications

  1. Popescu S, Popescu G, Bachan S, Zhang Z, Seay M, Gerstein M, et al. Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Proc Natl Acad Sci U S A. 2007;104:4730-5 pubmed
    ..Our results suggest that calcium functions through distinct CaM/CML proteins to regulate a wide range of targets and cellular activities. ..
  2. Kumar S, Mazumder M, Gupta N, Chattopadhyay S, Gourinath S. Crystal structure of Arabidopsis thaliana calmodulin7 and insight into its mode of DNA binding. FEBS Lett. 2016;590:3029-39 pubmed publisher
    ..It has been shown that Arabidopsis thaliana CaM7 (AtCaM7) interacts with Z-box DNA and functions as a transcription factor [Kushwaha R et al...
  3. Kushwaha R, Singh A, Chattopadhyay S. Calmodulin7 plays an important role as transcriptional regulator in Arabidopsis seedling development. Plant Cell. 2008;20:1747-59 pubmed publisher
    ..Here, we show that one of the four Arabidopsis thaliana CaM isoforms, CAM7, is a transcriptional regulator that directly interacts with the promoters of light-inducible genes and promotes ..
  4. Ihara Ohori Y, Nagano M, Muto S, Uchimiya H, Kawai Yamada M. Cell death suppressor Arabidopsis bax inhibitor-1 is associated with calmodulin binding and ion homeostasis. Plant Physiol. 2007;143:650-60 pubmed
    ..Furthermore, AtBI-1-overexpressing cells demonstrated an attenuated rise in cytosolic calcium following CPA or H2O2 treatment, suggesting that AtBI-1 affects ion homeostasis in plant cell death regulation. ..
  5. Tidow H, Poulsen L, Andreeva A, Knudsen M, Hein K, Wiuf C, et al. A bimodular mechanism of calcium control in eukaryotes. Nature. 2012;491:468-72 pubmed publisher
  6. Abbas N, Maurya J, Senapati D, Gangappa S, Chattopadhyay S. Arabidopsis CAM7 and HY5 physically interact and directly bind to the HY5 promoter to regulate its expression and thereby promote photomorphogenesis. Plant Cell. 2014;26:1036-52 pubmed publisher
    Arabidopsis thaliana CALMODULIN7 (CAM7), a unique member of the calmodulin gene family, plays a crucial role as a transcriptional regulator in seedling development...
  7. Abbas N, Chattopadhyay S. CAM7 and HY5 genetically interact to regulate root growth and abscisic acid responses. Plant Signal Behav. 2014;9:e29763 pubmed publisher
    b>CAM7, a member of CaM family in Arabidopsis, acts as a transcriptional regulator and enhances photomorphogenic growth and light regulated gene expression under various light conditions...
  8. Zielinski R. Characterization of three new members of the Arabidopsis thaliana calmodulin gene family: conserved and highly diverged members of the gene family functionally complement a yeast calmodulin null. Planta. 2002;214:446-55 pubmed
    ..Full-length cDNAs for each of the genes, Cam7, Cam8, and Cam9, were sequenced. Cam7 encodes a conventional 16.8-kDa, 148-amino-acid calmodulin protein (CaM)...
  9. Yamaguchi T, Aharon G, Sottosanto J, Blumwald E. Vacuolar Na+/H+ antiporter cation selectivity is regulated by calmodulin from within the vacuole in a Ca2+- and pH-dependent manner. Proc Natl Acad Sci U S A. 2005;102:16107-12 pubmed
    ..Taken together, the presence of a vacuolar calmodulin-like protein acting on the vacuolar-localized AtNHX1 C terminus in a Ca(2+)- pH-dependent manner suggests the presence of signaling entities acting within the vacuole. ..

More Information

Publications11

  1. Fischer C, Kugler A, Hoth S, Dietrich P. An IQ domain mediates the interaction with calmodulin in a plant cyclic nucleotide-gated channel. Plant Cell Physiol. 2013;54:573-84 pubmed publisher
    ..Since the IQ domain is conserved among plant CNGCs, this domain adds to the variability of Ca(2+)-dependent channel control mechanisms underlining the functional diversity within this multigene family. ..
  2. Tidow H, Hein K, Baekgaard L, Palmgren M, Nissen P. Expression, purification, crystallization and preliminary X-ray analysis of calmodulin in complex with the regulatory domain of the plasma-membrane Ca2+-ATPase ACA8. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010;66:361-3 pubmed publisher
    ..8, b = 70.0, c = 69.8 A, beta = 113.2 degrees. A complete data set was collected to 3.0 A resolution and structure determination is in progress in order to elucidate the mechanism of PMCA activation by calmodulin. ..