Gene Symbol: BAG6
Description: BCL-2-associated athanogene 6
Alias: ARABIDOPSIS THALIANA BCL-2-ASSOCIATED ATHANOGENE 6, ATBAG6, BCL-2-associated athanogene 6, T3F17.11, BCL-2-associated athanogene 6
Species: thale cress
Nishizawa A, Yabuta Y, Yoshida E, Maruta T, Yoshimura K, Shigeoka S. Arabidopsis heat shock transcription factor A2 as a key regulator in response to several types of environmental stress. Plant J. 2006;48:535-47 pubmed
..Our present results indicate that HsfA2 is a key regulator in the induction of the defence system under several types of environmental stress. ..
Li Y, Kabbage M, Liu W, Dickman M. Aspartyl Protease-Mediated Cleavage of BAG6 Is Necessary for Autophagy and Fungal Resistance in Plants. Plant Cell. 2016;28:233-47 pubmed publisher
..Previously we found that Arabidopsis thaliana BAG6 is required for basal immunity against the fungal phytopathogen Botrytis cinerea...
Kang C, Jung W, Kang Y, Kim J, Kim D, Jeong J, et al
. AtBAG6, a novel calmodulin-binding protein, induces programmed cell death in yeast and plants. Cell Death Differ. 2006;13:84-95 pubmed
Calmodulin (CaM) influences many cellular processes by interacting with various proteins. Here, we isolated AtBAG6, an Arabidopsis CaM-binding protein that contains a central BCL-2-associated athanogene (BAG) domain...
Li Y, Dickman M. Processing of AtBAG6 triggers autophagy and fungal resistance. Plant Signal Behav. 2016;11:e1175699 pubmed publisher
..Evaluating knockouts in Arabidopsis of individual BAG family members, we noted that Arabidopsis BAG6 (AtBAG6) knockout lines exhibited a pronounced enhancement of susceptibility to the necrotrophic fungal pathogen Botrytis ..
Doukhanina E, Chen S, van der Zalm E, Godzik A, Reed J, Dickman M. Identification and functional characterization of the BAG protein family in Arabidopsis thaliana. J Biol Chem. 2006;281:18793-801 pubmed
..We further show that plant BAG family members are also multifunctional and remarkably similar to their animal counterparts, as they regulate apoptosis-like processes ranging from pathogen attack to abiotic stress and development. ..