Gene Symbol: AT2G22370
Description: mediator of RNA polymerase II transcription subunit
Alias: F14M13.23, F14M13_23, MED18, mediator 18, mediator of RNA polymerase II transcription subunit
Species: thale cress
Kim Y, Zheng B, Yu Y, Won S, Mo B, Chen X. The role of Mediator in small and long noncoding RNA production in Arabidopsis thaliana. EMBO J. 2011;30:814-22 pubmed publisher
..This study expands the function of Mediator to include Pol II-mediated intergenic transcription and implicates a role of Mediator in genome stability. ..
Zheng Z, Guan H, Leal F, Grey P, Oppenheimer D. Mediator subunit18 controls flowering time and floral organ identity in Arabidopsis. PLoS ONE. 2013;8:e53924 pubmed publisher
..Here we show that in Arabidopsis thaliana, MEDIATOR SUBUNIT 18 (MED18) affects flowering time and floral organ formation through FLOWERING LOCUS C (FLC) and AGAMOUS (AG)...
Lai Z, Schluttenhofer C, Bhide K, Shreve J, Thimmapuram J, Lee S, et al
. MED18 interaction with distinct transcription factors regulates multiple plant functions. Nat Commun. 2014;5:3064 pubmed publisher
..Mechanisms of Mediator function are poorly understood. Here we show that Arabidopsis MED18 is a multifunctional protein regulating plant immunity, flowering time and responses to hormones through ..
Liao C, Lai Z, Lee S, Yun D, Mengiste T. Arabidopsis HOOKLESS1 Regulates Responses to Pathogens and Abscisic Acid through Interaction with MED18 and Acetylation of WRKY33 and ABI5 Chromatin. Plant Cell. 2016;28:1662-81 pubmed publisher
..Mediator, a eukaryotic transcription coregulatory complex, through direct interaction with mediator subunit 18 (MED18), with which it shares multiple functions...
Fallath T, Kidd B, Stiller J, Davoine C, Bjorklund S, Manners J, et al
. MEDIATOR18 and MEDIATOR20 confer susceptibility to Fusarium oxysporum in Arabidopsis thaliana. PLoS ONE. 2017;12:e0176022 pubmed publisher
..Mutants of MED18 and MED20 display down-regulation of genes associated with jasmonate signaling and biosynthesis while up-..