APG7

Summary

Gene Symbol: APG7
Description: ThiF family protein
Alias: ATAPG7, ATATG7, ATG7, AUTOPHAGY 7, AUTOPHAGY-RELATED 7, K15I22.10, K15I22_10, PEROXISOME UNUSUAL POSITIONING 4, PEUP4, ThiF family protein
Species: thale cress
Products:     APG7

Top Publications

  1. Lai Z, Wang F, Zheng Z, Fan B, Chen Z. A critical role of autophagy in plant resistance to necrotrophic fungal pathogens. Plant J. 2011;66:953-68 pubmed publisher
    ..These results strongly suggest that autophagy cooperates with jasmonate- and WRKY33-mediated signaling pathways in the regulation of plant defense responses to necrotrophic pathogens. ..
  2. Otegui M, Noh Y, Martínez D, Vila Petroff M, Staehelin L, Amasino R, et al. Senescence-associated vacuoles with intense proteolytic activity develop in leaves of Arabidopsis and soybean. Plant J. 2005;41:831-44 pubmed
    ..The presence of two types of vacuoles in senescing leaves could provide different lytic compartments for the dismantling of specific cellular components. The possible origin and functions of SAVs during leaf senescence are discussed. ..
  3. Yamaguchi M, Matoba K, Sawada R, Fujioka Y, Nakatogawa H, Yamamoto H, et al. Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7. Nat Struct Mol Biol. 2012;19:1250-6 pubmed publisher
    Autophagy requires ubiquitin-like Atg8 and Atg12 conjugation systems, where Atg7 has a critical role as the sole E1 enzyme...
  4. Doelling J, Walker J, Friedman E, Thompson A, Vierstra R. The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and senescence in Arabidopsis thaliana. J Biol Chem. 2002;277:33105-14 pubmed
    ..A single APG7 gene encodes the ATP-dependent activating enzyme that initiates both conjugation pathways...
  5. Thompson A, Doelling J, Suttangkakul A, Vierstra R. Autophagic nutrient recycling in Arabidopsis directed by the ATG8 and ATG12 conjugation pathways. Plant Physiol. 2005;138:2097-110 pubmed
    ..Using an Arabidopsis (Arabidopsis thaliana) atg7 mutant unable to ligate either tag, we previously showed that the ATG8/12 conjugation system is important for ..