AP3

Summary

Gene Symbol: AP3
Description: K-box region and MADS-box transcription factor family protein
Alias: APETALA 3, ATAP3, FLORAL HOMEOTIC PROTEIN APETALA 3, K-box region and MADS-box transcription factor family protein
Species: thale cress

Top Publications

  1. Goto K, Meyerowitz E. Function and regulation of the Arabidopsis floral homeotic gene PISTILLATA. Genes Dev. 1994;8:1548-60 pubmed
    ..a B function floral homeotic gene and acts together with the product of the other known B function gene, APETALA3 (AP3). We have cloned PI and determined the time and places of its expression in developing flowers...
  2. Riechmann J, Krizek B, Meyerowitz E. Dimerization specificity of Arabidopsis MADS domain homeotic proteins APETALA1, APETALA3, PISTILLATA, and AGAMOUS. Proc Natl Acad Sci U S A. 1996;93:4793-8 pubmed
    The MADS domain homeotic proteins APETALA1 (AP1), APETALA3 (AP3), PISTILLATA (PI), and AGAMOUS (AG) act in a combinatorial manner to specify the identity of Arabidopsis floral organs...
  3. Tzeng T, Liu H, Yang C. The C-terminal sequence of LMADS1 is essential for the formation of homodimers for B function proteins. J Biol Chem. 2004;279:10747-55 pubmed
    LMADS1, a lily (Lilium longiflorum) AP3 orthologue, contains the complete consensus sequence of the paleoAP3 (YGSHDLRLA) and PI-derived (YEFRVQPSQPNLH) motifs in the C-terminal region of the protein...
  4. Piwarzyk E, Yang Y, Jack T. Conserved C-terminal motifs of the Arabidopsis proteins APETALA3 and PISTILLATA are dispensable for floral organ identity function. Plant Physiol. 2007;145:1495-505 pubmed
    The B-class genes APETALA3 (AP3) and PISTILLATA (PI) in Arabidopsis (Arabidopsis thaliana) and their orthologs in other species have been the focus of studies to elucidate the development of petals and stamens in angiosperm flowers...
  5. Bowman J, Smyth D, Meyerowitz E. Genes directing flower development in Arabidopsis. Plant Cell. 1989;1:37-52 pubmed
    ..shift experiments indicate that the wild-type AP2 gene product acts at the time of primordium initiation; the AP3 product is active later...
  6. McGonigle B, Bouhidel K, Irish V. Nuclear localization of the Arabidopsis APETALA3 and PISTILLATA homeotic gene products depends on their simultaneous expression. Genes Dev. 1996;10:1812-21 pubmed
    The Arabidopsis APETALA3 (AP3) and PISTILLATA (PI) proteins are thought to act as transcription factors and are required for specifying floral organ identities...
  7. Moon Y, Jung J, Kang H, An G. Identification of a rice APETALA3 homologue by yeast two-hybrid screening. Plant Mol Biol. 1999;40:167-77 pubmed
    ..The sequence comparison indicated that OsMADS16 belongs to the AP3 family...
  8. Sridhar V, Surendrarao A, Liu Z. APETALA1 and SEPALLATA3 interact with SEUSS to mediate transcription repression during flower development. Development. 2006;133:3159-66 pubmed
  9. ÓMaoiléidigh D, Wuest S, Rae L, Raganelli A, Ryan P, Kwasniewska K, et al. Control of reproductive floral organ identity specification in Arabidopsis by the C function regulator AGAMOUS. Plant Cell. 2013;25:2482-503 pubmed publisher

More Information

Publications17

  1. Yang Y, Xiang H, Jack T. pistillata-5, an Arabidopsis B class mutant with strong defects in petal but not in stamen development. Plant J. 2003;33:177-88 pubmed
    The Arabidopsis floral organ identity genes APETALA3 (AP3) and PISTILLATA (PI) encode related DNA-binding proteins of the MADS family...
  2. Melzer R, Theissen G. Reconstitution of 'floral quartets' in vitro involving class B and class E floral homeotic proteins. Nucleic Acids Res. 2009;37:2723-36 pubmed publisher
    ..Here, we demonstrate that the class B floral homeotic proteins APETALA3 (AP3) and PISTILLATA (PI) do only weakly, at best, form floral-quartet-like structures on their own...
  3. Fang Z, Qi R, Li X, Liu Z. Ectopic expression of FaesAP3, a Fagopyrum esculentum (Polygonaceae) AP3 orthologous gene rescues stamen development in an Arabidopsis ap3 mutant. Gene. 2014;550:200-6 pubmed publisher
    Arabidopsis thaliana APETALA3 (AP3) and Antirrhinum majus DEFICIENS (DEF) MADS box genes are required to specify petal and stamen identity...
  4. Mara C, Huang T, Irish V. The Arabidopsis floral homeotic proteins APETALA3 and PISTILLATA negatively regulate the BANQUO genes implicated in light signaling. Plant Cell. 2010;22:690-702 pubmed publisher
    The Arabidopsis thaliana MADS box transcription factors APETALA3 (AP3) and PISTILLATA (PI) heterodimerize and are required to specify petal identity, yet many details of how this regulatory process is effected are unclear...
  5. Smaczniak C, Immink R, Muiño J, Blanvillain R, Busscher M, Busscher Lange J, et al. Characterization of MADS-domain transcription factor complexes in Arabidopsis flower development. Proc Natl Acad Sci U S A. 2012;109:1560-5 pubmed publisher
    ..show using affinity purification and mass spectrometry that five major floral homeotic MADS-domain proteins (AP1, AP3, PI, AG, and SEP3) interact in floral tissues as proposed in the "floral quartet" model...
  6. Wuest S, Ó Maoiléidigh D, Rae L, Kwasniewska K, Raganelli A, Hanczaryk K, et al. Molecular basis for the specification of floral organs by APETALA3 and PISTILLATA. Proc Natl Acad Sci U S A. 2012;109:13452-7 pubmed publisher
    ..underlying organ specification in plants, we studied the function of the homeotic selector genes APETALA3 (AP3) and PISTILLATA (PI), which control the formation of petals and stamens during Arabidopsis flower development...
  7. Sundström J, Engström P. Conifer reproductive development involves B-type MADS-box genes with distinct and different activities in male organ primordia. Plant J. 2002;31:161-9 pubmed
    ..form homodimers, and that DAL11 and DAL13 may form heterodimers with each other and with the Arabidopsis B-protein AP3, but not with PI, the second B-gene product in Arabidopsis...
  8. Hsu W, Yeh T, Huang K, Li J, Chen H, Yang C. AGAMOUS-LIKE13, a putative ancestor for the E functional genes, specifies male and female gametophyte morphogenesis. Plant J. 2014;77:1-15 pubmed publisher
    ..to SEP proteins, AGL13 is able to interact with AG to form quartet-like complexes (AGL13-AG)2 and interact with AG-AP3-PI to form a higher-order heterotetrameric complex (AGL13-AG-AP3-PI)...