Gene Symbol: AGO7
Description: Argonaute family protein
Alias: ARGONAUTE7, F10D13.11, F10D13_11, ZIP, ZIPPY, Argonaute family protein
Species: thale cress

Top Publications

  1. Fahlgren N, Montgomery T, Howell M, Allen E, Dvorak S, Alexander A, et al. Regulation of AUXIN RESPONSE FACTOR3 by TAS3 ta-siRNA affects developmental timing and patterning in Arabidopsis. Curr Biol. 2006;16:939-44 pubmed
    ..We show that the juvenile-to-adult phase transition is normally suppressed by TAS3 ta-siRNAs, in an ARGONAUTE7-dependent manner, through negative regulation of ARF3 mRNA...
  2. Xu L, Yang L, Pi L, Liu Q, Ling Q, Wang H, et al. Genetic interaction between the AS1-AS2 and RDR6-SGS3-AGO7 pathways for leaf morphogenesis. Plant Cell Physiol. 2006;47:853-63 pubmed
    ..We show that plants carrying rdr6, suppressor of gene silencing3 (sgs3) or zippy (zip, also called ago7) in combination with as1 or as2 demonstrate severe morphological defects, and the double ..
  3. Jouannet V, Moreno A, Elmayan T, Vaucheret H, Crespi M, Maizel A. Cytoplasmic Arabidopsis AGO7 accumulates in membrane-associated siRNA bodies and is required for ta-siRNA biogenesis. EMBO J. 2012;31:1704-13 pubmed publisher
    Formation of trans-acting small interfering RNAs (ta-siRNAs) from the TAS3 precursor is triggered by the AGO7/miR390 complex, which primes TAS3 for conversion into double-stranded RNA by the RNA-dependent RNA polymerase RDR6 and SGS3...
  4. Hunter C, Sun H, Poethig R. The Arabidopsis heterochronic gene ZIPPY is an ARGONAUTE family member. Curr Biol. 2003;13:1734-9 pubmed
    ..ZIP encodes ARGONAUTE7 (AGO7), one of ten members of the ARGONAUTE family in Arabidopsis...
  5. Katiyar Agarwal S, Gao S, Vivian Smith A, Jin H. A novel class of bacteria-induced small RNAs in Arabidopsis. Genes Dev. 2007;21:3123-34 pubmed
    ..requires PIWI subfamily proteins, generation of AtlsiRNA-1 requires DCL1, DCL4, and the ARGONAUTE subfamily protein AGO7. It also depends on HYL1, HEN1, HST1, RDR6, and Pol IV...
  6. Endo Y, Iwakawa H, Tomari Y. Arabidopsis ARGONAUTE7 selects miR390 through multiple checkpoints during RISC assembly. EMBO Rep. 2013;14:652-8 pubmed publisher
    Plant ARGONAUTE7 (AGO7) assembles RNA-induced silencing complex (RISC) specifically with miR390 and regulates the auxin-signalling pathway via production of TAS3 trans-acting siRNAs (tasiRNAs)...
  7. Brosseau C, Moffett P. Functional and Genetic Analysis Identify a Role for Arabidopsis ARGONAUTE5 in Antiviral RNA Silencing. Plant Cell. 2015;27:1742-54 pubmed publisher
    ..In agreement with functional assays, we show that Potexvirus infection induces AGO5 expression and that both AGO2 and AGO5 are required for full restriction of PVX infection in systemic tissues of Arabidopsis. ..
  8. Montgomery T, Howell M, Cuperus J, Li D, Hansen J, Alexander A, et al. Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3 trans-acting siRNA formation. Cell. 2008;133:128-41 pubmed publisher
    ..Here, we show that miR390-ARGONAUTE7 complexes function in distinct cleavage or noncleavage modes at two target sites in TAS3a transcripts...
  9. Qu F, Ye X, Morris T. Arabidopsis DRB4, AGO1, AGO7, and RDR6 participate in a DCL4-initiated antiviral RNA silencing pathway negatively regulated by DCL1. Proc Natl Acad Sci U S A. 2008;105:14732-7 pubmed publisher
    ..We also implicate DRB4 in antiviral RNA silencing. Finally, we show that both AGO1 and AGO7 function to ensure efficient clearance of viral RNAs and establish that AGO1 is capable of targeting viral RNAs ..

More Information


  1. Tantikanjana T, Rizvi N, Nasrallah M, Nasrallah J. A dual role for the S-locus receptor kinase in self-incompatibility and pistil development revealed by an Arabidopsis rdr6 mutation. Plant Cell. 2009;21:2642-54 pubmed publisher
  2. Carbonell A, Fahlgren N, Garcia Ruiz H, Gilbert K, Montgomery T, Nguyen T, et al. Functional analysis of three Arabidopsis ARGONAUTES using slicer-defective mutants. Plant Cell. 2012;24:3613-29 pubmed publisher
    ..Complementation analyses in ago mutant plants revealed that the catalytic residues of AGO1, AGO2, and AGO7 are required to restore the defects of Arabidopsis ago1-25, ago2-1, and zip-1 (AGO7-defective) mutants, ..