Gene Symbol: AFB3
Description: auxin signaling F-box 3
Alias: F13K23.7, F13K23_7, auxin signaling F-box 3, auxin signaling F-box 3
Species: thale cress

Top Publications

  1. Navarro L, Dunoyer P, Jay F, Arnold B, Dharmasiri N, Estelle M, et al. A plant miRNA contributes to antibacterial resistance by repressing auxin signaling. Science. 2006;312:436-9 pubmed
    ..a plant microRNA (miRNA) that negatively regulates messenger RNAs for the F-box auxin receptors TIR1, AFB2, and AFB3. Repression of auxin signaling restricts P...
  2. Dharmasiri N, Dharmasiri S, Weijers D, Lechner E, Yamada M, Hobbie L, et al. Plant development is regulated by a family of auxin receptor F box proteins. Dev Cell. 2005;9:109-19 pubmed
    ..Correspondingly, all TIR1/AFB proteins interact with BDL, and BDL is stabilized in triple mutant plants. Our results indicate that TIR1 and the AFB proteins collectively mediate auxin responses throughout plant development. ..
  3. Vidal E, Moyano T, Riveras E, Contreras L pez O, Guti rrez R. Systems approaches map regulatory networks downstream of the auxin receptor AFB3 in the nitrate response of Arabidopsis thaliana roots. Proc Natl Acad Sci U S A. 2013;110:12840-5 pubmed publisher
    ..We previously reported a role for AFB3 in coordinating primary and lateral root growth to nitrate availability...
  4. Takato S, Kakei Y, Mitsui M, Ishida Y, Suzuki M, Yamazaki C, et al. Auxin signaling through SCFTIR1/AFBs mediates feedback regulation of IAA biosynthesis. Biosci Biotechnol Biochem. 2017;81:1320-1326 pubmed publisher
    ..These observations suggest that the endogenous IAA levels are regulated by auxin biosynthesis in a feedback manner, and the Aux/IAA and SCFTIR1/AFB-mediated auxin-signaling pathway regulates the expression of YUC genes. ..
  5. Dharmasiri N, Dharmasiri S, Estelle M. The F-box protein TIR1 is an auxin receptor. Nature. 2005;435:441-5 pubmed
    ..Finally, TIR1 synthesized in insect cells binds Aux/IAA proteins in an auxin-dependent manner. Together, these results indicate that TIR1 is an auxin receptor that mediates Aux/IAA degradation and auxin-regulated transcription. ..
  6. Cecchetti V, Altamura M, Falasca G, Costantino P, Cardarelli M. Auxin regulates Arabidopsis anther dehiscence, pollen maturation, and filament elongation. Plant Cell. 2008;20:1760-74 pubmed publisher
    ..In agreement with the timing of auxin effects, the TIR1, AFB1, AFB2, and AFB3 auxin receptor-encoding genes are transcribed in anthers only during late stages of development starting at the end ..
  7. Vidal E, Alvarez J, Gutierrez R. Nitrate regulation of AFB3 and NAC4 gene expression in Arabidopsis roots depends on NRT1.1 nitrate transport function. Plant Signal Behav. 2014;9:e28501 pubmed
    ..We found that gene expression in response to nitrate treatment of the AFB3 auxin receptor and its target, the NAC4 transcription factor depends on the nitrate transport function of NRT1.1...
  8. Vidal E, Araus V, Lu C, Parry G, Green P, Coruzzi G, et al. Nitrate-responsive miR393/AFB3 regulatory module controls root system architecture in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2010;107:4477-82 pubmed publisher
    ..code for a basic helix-loop-helix (bHLH) transcription factor and for the auxin receptors TIR1, AFB1, AFB2, and AFB3. However, only AFB3 was regulated by nitrate in roots under our experimental conditions...