Gene Symbol: ADL6
Description: dynamin-like protein 6
Alias: DRP2A, DYNAMIN-RELATED PROTEIN 2A, F14N23.17, F14N23_17, dynamin-like protein 6, dynamin-like protein 6
Species: thale cress
Lee M, Lee S, Kim H, Jin J, Kim D, Hwang I. A WD40 repeat protein, Arabidopsis Sec13 homolog 1, may play a role in vacuolar trafficking by controlling the membrane association of AtDRP2A. Mol Cells. 2006;22:210-9 pubmed
Dynamin-related protein 2A (AtDRP2A, formally ADL6), a member of the dynamin family, is critical for protein trafficking from the TGN to the central vacuole...
Lee S, Jin J, Song J, Min M, Park D, Kim Y, et al
. The intermolecular interaction between the PH domain and the C-terminal domain of Arabidopsis dynamin-like 6 determines lipid binding specificity. J Biol Chem. 2002;277:31842-9 pubmed
..Here we investigate the nature of membrane binding of the Arabidopsis dynamin-like 6 (ADL6) involved in vesicle trafficking from the trans-Golgi network to the central vacuole...
Lam B, Sage T, Bianchi F, Blumwald E. Regulation of ADL6 activity by its associated molecular network. Plant J. 2002;31:565-76 pubmed
..In this study we demonstrate that ADL6 (Arabidopsis dynamin-like protein 6), due to its domain arrangement, behaves similarly to the animal dynamins...
Backues S, Korasick D, Heese A, Bednarek S. The Arabidopsis dynamin-related protein2 family is essential for gametophyte development. Plant Cell. 2010;22:3218-31 pubmed publisher
..Gametophytes lacking both DRP2A and DRP2B were inviable, arresting prior to the first mitotic division in both male and female gametogenesis...
Taylor N. A role for Arabidopsis dynamin related proteins DRP2A/B in endocytosis; DRP2 function is essential for plant growth. Plant Mol Biol. 2011;76:117-29 pubmed publisher
..that have all the domains essential for function in the animal dynamins, Dynamin Related Proteins 2A and 2B (DRP2A and 2B). These proteins show very high sequence identity and are both expressed throughout the plant...
Jin J, Kim Y, Kim S, Lee S, Kim D, Cheong G, et al
. A new dynamin-like protein, ADL6, is involved in trafficking from the trans-Golgi network to the central vacuole in Arabidopsis. Plant Cell. 2001;13:1511-26 pubmed
..Here we report the identification of a new dynamin homolog in Arabidopsis named Arabidopsis dynamin-like 6 (ADL6)...
Atmodjo M, Sakuragi Y, Zhu X, Burrell A, Mohanty S, Atwood J, et al
. Galacturonosyltransferase (GAUT)1 and GAUT7 are the core of a plant cell wall pectin biosynthetic homogalacturonan:galacturonosyltransferase complex. Proc Natl Acad Sci U S A. 2011;108:20225-30 pubmed publisher
Huang J, Fujimoto M, Fujiwara M, Fukao Y, Arimura S, Tsutsumi N. Arabidopsis dynamin-related proteins, DRP2A and DRP2B, function coordinately in post-Golgi trafficking. Biochem Biophys Res Commun. 2015;456:238-44 pubmed publisher
..In Arabidopsis thaliana, two paralogous land plant-specific type DRPs, DRP2A and DRP2B, are thought to participate in the regulation of post-Golgi trafficking...
Chaparro Garcia A, Schwizer S, Sklenar J, Yoshida K, Petre B, Bos J, et al
. Phytophthora infestans RXLR-WY Effector AVR3a Associates with Dynamin-Related Protein 2 Required for Endocytosis of the Plant Pattern Recognition Receptor FLS2. PLoS ONE. 2015;10:e0137071 pubmed publisher
..We conclude that AVR3a is a multifunctional effector that can suppress BAK1/SERK3-mediated immunity through at least two different pathways. ..