Gene Symbol: ACT2
Description: actin 2
Species: thale cress
Products:     ACT2

Top Publications

  1. Kandasamy M, McKinney E, Meagher R. A single vegetative actin isovariant overexpressed under the control of multiple regulatory sequences is sufficient for normal Arabidopsis development. Plant Cell. 2009;21:701-18 pubmed publisher
    ..Arabidopsis thaliana encodes three vegetative actins, ACT2, ACT7, and ACT8, in two ancient and highly divergent subclasses...
  2. Lin W, Wang Y, Mueller Roeber B, Brearley C, Xu Z, Xue H. At5PTase13 modulates cotyledon vein development through regulating auxin homeostasis. Plant Physiol. 2005;139:1677-91 pubmed
    ..The At5pt13-1 mutant was also less sensitive to auxin inhibition of root elongation. These results suggest that At5PTase13 regulates the homeostasis of auxin, a key hormone controlling vascular development in plants. ..
  3. Balasubramanian R, Karve A, Kandasamy M, Meagher R, Moore B. A role for F-actin in hexokinase-mediated glucose signaling. Plant Physiol. 2007;145:1423-34 pubmed
    ..We also demonstrate that Glc treatment of Arabidopsis seedlings rapidly and reversibly disrupts fine mesh actin filaments. The possible roles of actin in HXK-dependent Glc signaling are discussed. ..
  4. Dunaeva M, Adamska I. Identification of genes expressed in response to light stress in leaves of Arabidopsis thaliana using RNA differential display. Eur J Biochem. 2001;268:5521-9 pubmed
    ..encoded cytoplasmic proteins with assigned identities, such as ERD15 (early responsive to dehydration), ACT2 (actin 2), LEA14 (late embryogenesis abundant) and MT1a (metallothionein class 1a), respectively...
  5. Gilliland L, Kandasamy M, Pawloski L, Meagher R. Both vegetative and reproductive actin isovariants complement the stunted root hair phenotype of the Arabidopsis act2-1 mutation. Plant Physiol. 2002;130:2199-209 pubmed
    The ACT2 gene, encoding one of eight actin isovariants in Arabidopsis, is the most strongly expressed actin gene in vegetative tissues...
  6. Kiefer C, Claes A, Nzayisenga J, Pietra S, Stanislas T, Hüser A, et al. Arabidopsis AIP1-2 restricted by WER-mediated patterning modulates planar polarity. Development. 2015;142:151-61 pubmed publisher
    ..Hence, our findings reveal AIP1-2, expressed under control of the WER-dependent patterning machinery and the ethylene signalling pathway, as a modulator of actin-mediated planar polarity. ..
  7. Kunieda T, Mitsuda N, Ohme Takagi M, Takeda S, Aida M, Tasaka M, et al. NAC family proteins NARS1/NAC2 and NARS2/NAM in the outer integument regulate embryogenesis in Arabidopsis. Plant Cell. 2008;20:2631-42 pubmed publisher
    ..Our findings suggest that there is an intertissue communication between the embryo and the maternal integument. ..
  8. Kandasamy M, McKinney E, Meagher R. Functional nonequivalency of actin isovariants in Arabidopsis. Mol Biol Cell. 2002;13:251-61 pubmed
    ..expressed a reproductive actin, ACT1, under the control of the regulatory sequences of a vegetative actin gene, ACT2. In the wild-type plants, ACT1 is predominantly expressed in the mature pollen, growing pollen tubes, and ovules, ..
  9. Gehl C, Kaufholdt D, Hamisch D, Bikker R, Kudla J, Mendel R, et al. Quantitative analysis of dynamic protein-protein interactions in planta by a floated-leaf luciferase complementation imaging (FLuCI) assay using binary Gateway vectors. Plant J. 2011;67:542-53 pubmed publisher

More Information


  1. Ringli C, Baumberger N, Keller B. The Arabidopsis root hair mutants der2-der9 are affected at different stages of root hair development. Plant Cell Physiol. 2005;46:1046-53 pubmed
    ..A double mutant analysis with the short root hair actin2 mutant der1-2 confirmed that the der mutants are disturbed at different time points of root hair formation...
  2. Li G, Xue H. Arabidopsis PLDzeta2 regulates vesicle trafficking and is required for auxin response. Plant Cell. 2007;19:281-95 pubmed
    ..These results suggest that PLDzeta2 and PA are required for the normal cycling of PIN2-containing vesicles as well as for function in auxin transport and distribution, and hence auxin responses. ..
  3. Kusano H, Testerink C, Vermeer J, Tsuge T, Shimada H, Oka A, et al. The Arabidopsis Phosphatidylinositol Phosphate 5-Kinase PIP5K3 is a key regulator of root hair tip growth. Plant Cell. 2008;20:367-80 pubmed publisher
    ..These results provide evidence that PIP5K3 is involved in localizing PtdIns(4,5)P2 to the elongating root hair apex and is a key regulator of the machinery that initiates and promotes root hair tip growth. ..
  4. Brenner W, Romanov G, Köllmer I, Bürkle L, Schmülling T. Immediate-early and delayed cytokinin response genes of Arabidopsis thaliana identified by genome-wide expression profiling reveal novel cytokinin-sensitive processes and suggest cytokinin action through transcriptional cascades. Plant J. 2005;44:314-33 pubmed
    ..Taken together, we present a genome-wide view of changes in cytokinin-responsive transcript abundance of genes that might be functionally relevant for the many biological processes that are governed by cytokinins. ..
  5. Wallström S, Aidemark M, Escobar M, Rasmusson A. An alternatively spliced domain of the NDC1 NAD(P)H dehydrogenase gene strongly influences the expression of the ACTIN2 reference gene in Arabidopsis thaliana. Plant Sci. 2012;183:190-6 pubmed publisher
    ..Also for other reference genes, strong expressional effects were observed when comparing various mutants and wildtypes in microarray databases. ..
  6. Yang X, Xu Z, Xue H. Arabidopsis membrane steroid binding protein 1 is involved in inhibition of cell elongation. Plant Cell. 2005;17:116-31 pubmed
    ..This study demonstrates the functional roles of a steroid binding protein in growth regulation in higher plants. ..
  7. Tepperman J, Hwang Y, Quail P. phyA dominates in transduction of red-light signals to rapidly responding genes at the initiation of Arabidopsis seedling de-etiolation. Plant J. 2006;48:728-42 pubmed
  8. Lu Y, Steichen J, Yao J, Sharkey T. The role of cytosolic alpha-glucan phosphorylase in maltose metabolism and the comparison of amylomaltase in Arabidopsis and Escherichia coli. Plant Physiol. 2006;142:878-89 pubmed
    ..Other plant species also contain SHG, DPE2, and alpha-glucan phosphorylase, so this pathway for maltose metabolism may be widespread among plants. ..