ACS6

Summary

Gene Symbol: ACS6
Description: 1-aminocyclopropane-1-carboxylic acid (acc) synthase 6
Alias: 1-aminocyclopropane-1-carboxylic acid (acc) synthase 6, ATACS6, F8L21.70, F8L21_70, 1-aminocyclopropane-1-carboxylic acid (acc) synthase 6
Species: thale cress

Top Publications

  1. Arteca J, Arteca R. A multi-responsive gene encoding 1-aminocyclopropane-1-carboxylate synthase (ACS6) in mature Arabidopsis leaves. Plant Mol Biol. 1999;39:209-19 pubmed
    ..the involvement of ethylene in touch-induced responses, we identified and characterized an Arabidopsis cDNA (ACS6) encoding 1-aminocyclopropane-1-carboxylic acid (ACC) synthase which is an important regulatory enzyme in the ..
  2. Vandenbussche F, Vriezen W, Smalle J, Laarhoven L, Harren F, Van Der Straeten D. Ethylene and auxin control the Arabidopsis response to decreased light intensity. Plant Physiol. 2003;133:517-27 pubmed
    ..gene IAA3 and a protein with similarity to AUX22 and the 1-aminocyclopropane-1-carboxylic acid synthase genes ACS6, ACS8, and ACS9 that are involved in ethylene biosynthesis...
  3. Han L, Li G, Yang K, Mao G, Wang R, Liu Y, et al. Mitogen-activated protein kinase 3 and 6 regulate Botrytis cinerea-induced ethylene production in Arabidopsis. Plant J. 2010;64:114-27 pubmed publisher
    ..mitogen-activated protein kinase (MAPK) was previously shown to regulate the stability of ACS2 and ACS6, two type I ACS isozymes (1-amino-cyclopropane-1-carboxylic acid synthase)...
  4. Tsuchisaka A, Theologis A. Heterodimeric interactions among the 1-amino-cyclopropane-1-carboxylate synthase polypeptides encoded by the Arabidopsis gene family. Proc Natl Acad Sci U S A. 2004;101:2275-80 pubmed
    ..Nonfunctional heterodimerization may also play a regulatory role during the plant life cycle. ..
  5. Joo S, Liu Y, Lueth A, Zhang S. MAPK phosphorylation-induced stabilization of ACS6 protein is mediated by the non-catalytic C-terminal domain, which also contains the cis-determinant for rapid degradation by the 26S proteasome pathway. Plant J. 2008;54:129-40 pubmed publisher
    ..Recently, we found that ACS2 and ACS6, two isoforms of the Arabidopsis ACS family, are substrates of a stress-responsive mitogen-activated protein kinase ..
  6. Li G, Meng X, Wang R, Mao G, Han L, Liu Y, et al. Dual-level regulation of ACC synthase activity by MPK3/MPK6 cascade and its downstream WRKY transcription factor during ethylene induction in Arabidopsis. PLoS Genet. 2012;8:e1002767 pubmed publisher
    ..Previously, we reported the involvement of ACS2 and ACS6, two Type I ACS isoforms, in Botrytis cinerea-induced ethylene biosynthesis and their regulation at the protein ..
  7. Peng H, Lin T, Wang N, Shih M. Differential expression of genes encoding 1-aminocyclopropane-1-carboxylate synthase in Arabidopsis during hypoxia. Plant Mol Biol. 2005;58:15-25 pubmed
    ..Our data showed that the expression of 4 of the 12 Arabidopsis ACS genes, ACS2, ACS6, ACS7, and ACS9, is induced during hypoxia with three distinct patterns...
  8. Yamagami T, Tsuchisaka A, Yamada K, Haddon W, Harden L, Theologis A. Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family. J Biol Chem. 2003;278:49102-12 pubmed
    ..It is proposed that biochemically diverse ACS isozymes function in unique cellular environments for the biosynthesis of C2H4, permitting the signaling molecule to exert its unique effects in a tissue- or cell-specific fashion. ..
  9. Skottke K, Yoon G, Kieber J, DeLong A. Protein phosphatase 2A controls ethylene biosynthesis by differentially regulating the turnover of ACC synthase isoforms. PLoS Genet. 2011;7:e1001370 pubmed publisher
    ..Genetic analysis reveals that ethylene overproduction in PP2A-deficient plants requires ACS2 and ACS6, genes that encode ACS proteins known to be stabilized by phosphorylation, and proteolytic turnover of the ACS6 ..

More Information

Publications20

  1. Luo X, Chen Z, Gao J, Gong Z. Abscisic acid inhibits root growth in Arabidopsis through ethylene biosynthesis. Plant J. 2014;79:44-55 pubmed publisher
    ..Two ABA-activated calcium-dependent protein kinases, CPK4 and CPK11, phosphorylate the C-terminus of ACS6 and increase the stability of ACS6 in ethylene biosynthesis...
  2. Devoto A, Ellis C, Magusin A, Chang H, Chilcott C, Zhu T, et al. Expression profiling reveals COI1 to be a key regulator of genes involved in wound- and methyl jasmonate-induced secondary metabolism, defence, and hormone interactions. Plant Mol Biol. 2005;58:497-513 pubmed
    ..These results indicate that COI1 plays a pivotal role in wound- and JA signalling. ..
  3. Ludwikow A, Cieśla A, Kasprowicz Maluśki A, Mituła F, Tajdel M, Gałgański Ł, et al. Arabidopsis protein phosphatase 2C ABI1 interacts with type I ACC synthases and is involved in the regulation of ozone-induced ethylene biosynthesis. Mol Plant. 2014;7:960-976 pubmed publisher
    ..We found that ABI1 interacts with ACS6 and dephosphorylates its C-terminal fragment, a target of the stress-responsive mitogen-activated protein kinase, ..
  4. Babula D, Misztal L, Jakubowicz M, Kaczmarek M, Nowak W, Sadowski J. Genes involved in biosynthesis and signalisation of ethylene in Brassica oleracea and Arabidopsis thaliana: identification and genome comparative mapping of specific gene homologues. Theor Appl Genet. 2006;112:410-20 pubmed
    ..thaliana was followed by the identification of homologues to ACS2, ACS6 and ACS7 in the B. oleracea database...
  5. Schellingen K, Van Der Straeten D, Vandenbussche F, Prinsen E, Remans T, Vangronsveld J, et al. Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression. BMC Plant Biol. 2014;14:214 pubmed publisher
    ..ACC synthesis is the rate-limiting step in ethylene biosynthesis, and transcript levels of both ACS2 and ACS6 showed the highest increase and became the most abundant isoforms after Cd exposure, suggesting their importance in ..
  6. Miller J, Arteca R, Pell E. Senescence-associated gene expression during ozone-induced leaf senescence in Arabidopsis. Plant Physiol. 1999;120:1015-24 pubmed
    ..and BCB (blue copper-binding protein) were induced within 2 to 4 d of O(3) treatment; SAG18, SAG20, and ACS6 (ACC synthase) were induced within 4 to 6 d; and CCH (copper chaperone) was induced within 6 to 8 d...
  7. Catalá R, López Cobollo R, Mar Castellano M, Angosto T, Alonso J, Ecker J, et al. The Arabidopsis 14-3-3 protein RARE COLD INDUCIBLE 1A links low-temperature response and ethylene biosynthesis to regulate freezing tolerance and cold acclimation. Plant Cell. 2014;26:3326-42 pubmed publisher
    ..All these data indicate that RCI1A connects the low-temperature response with ET biosynthesis to modulate constitutive freezing tolerance and cold acclimation in Arabidopsis. ..
  8. Yoon G, Kieber J. 14-3-3 regulates 1-aminocyclopropane-1-carboxylate synthase protein turnover in Arabidopsis. Plant Cell. 2013;25:1016-28 pubmed publisher
  9. Etchells J, Provost C, Turner S. Plant vascular cell division is maintained by an interaction between PXY and ethylene signalling. PLoS Genet. 2012;8:e1002997 pubmed publisher
    ..We propose a model whereby vascular cell division is regulated both by PXY signalling and ethylene/ERF signalling. Under normal circumstances, however, PXY signalling acts to repress the ethylene/ERF pathway. ..
  10. Song C, Steinebrunner I, Wang X, Stout S, Roux S. Extracellular ATP induces the accumulation of superoxide via NADPH oxidases in Arabidopsis. Plant Physiol. 2006;140:1222-32 pubmed
    ..Together, these data suggest a possible role for extracellular ATP as a signal potentially in wound and stress responses. ..
  11. Datta R, Kumar D, Sultana A, Hazra S, Bhattacharyya D, Chattopadhyay S. Glutathione Regulates 1-Aminocyclopropane-1-Carboxylate Synthase Transcription via WRKY33 and 1-Aminocyclopropane-1-Carboxylate Oxidase by Modulating Messenger RNA Stability to Induce Ethylene Synthesis during Stress. Plant Physiol. 2015;169:2963-81 pubmed publisher
    ..Arabidopsis thaliana) plants with enhanced GSH content (AtECS) exhibited remarkable up-regulation of ACS2, ACS6, and ACO1 at transcript as well as protein levels, while they were down-regulated in the GSH-depleted phytoalexin ..