Gene Symbol: ABH1
Description: ARM repeat superfamily protein
Species: thale cress
Products:     ABH1

Top Publications

  1. Bush M, Hutchins A, Jones A, Naldrett M, Jarmolowski A, Lloyd C, et al. Selective recruitment of proteins to 5' cap complexes during the growth cycle in Arabidopsis. Plant J. 2009;59:400-12 pubmed publisher
    ..to be composed of only three major proteins: eIF4isoE, which is primarily a cytoplasmic protein, and eIF4E and CBP80, which accumulate in the nucleus...
  2. Christie M, Croft L, Carroll B. Intron splicing suppresses RNA silencing in Arabidopsis. Plant J. 2011;68:159-67 pubmed publisher
    ..This intron suppression of transgene silencing requires efficient intron splicing and is dependent on ABH1, the Arabidopsis orthologue of human cap-binding protein 80.
  3. Hugouvieux V, Kwak J, Schroeder J. An mRNA cap binding protein, ABH1, modulates early abscisic acid signal transduction in Arabidopsis. Cell. 2001;106:477-87 pubmed
    ..We have isolated a recessive ABA hypersensitive mutant, abh1, that shows hormone specificity to ABA...
  4. Raczynska K, Simpson C, Ciesiolka A, Szewc L, Lewandowska D, McNicol J, et al. Involvement of the nuclear cap-binding protein complex in alternative splicing in Arabidopsis thaliana. Nucleic Acids Res. 2010;38:265-78 pubmed publisher
    ..Splicing profiles were determined in wild type plants, the cbp20 and cbp80(abh1) single mutants and the cbp20/80 double mutant...
  5. Hugouvieux V, Murata Y, Young J, Kwak J, Mackesy D, Schroeder J. Localization, ion channel regulation, and genetic interactions during abscisic acid signaling of the nuclear mRNA cap-binding protein, ABH1. Plant Physiol. 2002;130:1276-87 pubmed
    ..We recently characterized a new Arabidopsis mutant, abh1, which shows ABA-hypersensitive regulation of seed germination, stomatal closing, and cytosolic calcium increases ..
  6. Wang L, Song X, Gu L, Li X, Cao S, Chu C, et al. NOT2 proteins promote polymerase II-dependent transcription and interact with multiple MicroRNA biogenesis factors in Arabidopsis. Plant Cell. 2013;25:715-27 pubmed publisher
    ..NOT2b protein interacts with polymerase II and other miRNA processing factors, including two cap binding proteins, CBP80/ABH1, CBP20, and SERRATE (SE)...
  7. Bezerra I, Michaels S, Schomburg F, Amasino R. Lesions in the mRNA cap-binding gene ABA HYPERSENSITIVE 1 suppress FRIGIDA-mediated delayed flowering in Arabidopsis. Plant J. 2004;40:112-9 pubmed
    ..the mutations are caused by lesions in the gene encoding the large subunit of the nuclear mRNA cap-binding protein, ABH1 (ABA hypersensitive1)...
  8. Laubinger S, Sachsenberg T, Zeller G, Busch W, Lohmann J, R├Ątsch G, et al. Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2008;105:8795-800 pubmed publisher
    ..noted before that the morphological appearance of weak se mutants is reminiscent of plants with mutations in ABH1/CBP80 and CBP20, which encode the two subunits of the nuclear cap-binding complex...
  9. Kim S, Yang J, Xu J, Jang I, Prigge M, Chua N. Two cap-binding proteins CBP20 and CBP80 are involved in processing primary MicroRNAs. Plant Cell Physiol. 2008;49:1634-44 pubmed publisher
    ..Here, we show that cbp20 and cbp80 mutants have reduced miRNA levels and increased pri-miRNA levels...

More Information


  1. Kuhn J, Breton G, Schroeder J. mRNA metabolism of flowering-time regulators in wild-type Arabidopsis revealed by a nuclear cap binding protein mutant, abh1. Plant J. 2007;50:1049-62 pubmed
    ..of flowering-time regulators in wild-type Arabidopsis plants, which were revealed by an early flowering mutation, abh1, in an Arabidopsis nuclear mRNA cap-binding protein...
  2. Kierzkowski D, Kmieciak M, Piontek P, Wojtaszek P, Szweykowska Kulinska Z, Jarmolowski A. The Arabidopsis CBP20 targets the cap-binding complex to the nucleus, and is stabilized by CBP80. Plant J. 2009;59:814-25 pubmed publisher
    ..transport of two subunits of the Arabidopsis thaliana cap-binding protein complex (AtCBC): AtCBP20 and AtCBP80. Using CFP/YFP-tagged proteins, we show that transport of AtCBC from the cytoplasm to the nucleus in the plant ..
  3. Daszkowska Golec A, Wojnar W, Rosikiewicz M, Szarejko I, Maluszynski M, Szweykowska Kulinska Z, et al. Arabidopsis suppressor mutant of abh1 shows a new face of the already known players: ABH1 (CBP80) and ABI4-in response to ABA and abiotic stresses during seed germination. Plant Mol Biol. 2013;81:189-209 pubmed publisher
    ..We used a genetic approach of a suppressor screening in order to decipher the interaction between ABH1 (CBP80) and other components of ABA signaling...
  4. Raczynska K, Stepien A, Kierzkowski D, Kalak M, Bajczyk M, McNicol J, et al. The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana. Nucleic Acids Res. 2014;42:1224-44 pubmed publisher
    ..Here we show that both subunits of AtCBC (AtCBP20 and AtCBP80) interact with SERRATE (AtSE), a protein involved in the microRNA biogenesis pathway...
  5. Kong X, Ma L, Yang L, Chen Q, Xiang N, Yang Y, et al. Quantitative proteomics analysis reveals that the nuclear cap-binding complex proteins arabidopsis CBP20 and CBP80 modulate the salt stress response. J Proteome Res. 2014;13:2495-510 pubmed publisher
    The cap-binding proteins CBP20 and CBP80 have well-established roles in RNA metabolism and plant growth and development...
  6. Liu J, Jung C, Xu J, Wang H, Deng S, Bernad L, et al. Genome-wide analysis uncovers regulation of long intergenic noncoding RNAs in Arabidopsis. Plant Cell. 2012;24:4333-45 pubmed publisher
    ..Further analysis of transcriptome data in 11 mutants uncovered SERRATE, CAP BINDING PROTEIN20 (CBP20), and CBP80 as regulators of lincRNA expression and biogenesis...
  7. Daszkowska Golec A, Chorazy E, Maluszynski M, Szarejko I. Towards the identification of new genes involved in ABA-dependent abiotic stresses using Arabidopsis suppressor mutants of abh1 hypersensitivity to ABA during seed germination. Int J Mol Sci. 2013;14:13403-32 pubmed publisher
    ..Using the abh1 (ABA hypersensitive 1) insertional mutant as a parental line for EMS mutagenesis, we selected several mutants with suppressed ..