glbN

Summary

Gene Symbol: glbN
Description: cyanoglobin
Species: synechocystis sp. pcc 6803

Top Publications

  1. ncbi Cloning, expression, purification, and preliminary characterization of a putative hemoglobin from the cyanobacterium Synechocystis sp. PCC 6803
    N L Scott
    Department of Chemistry and the Center for Biomolecular Structure and Function, The Pennsylvania State University, University Park 16802, USA
    Protein Sci 9:587-97. 2000
  2. ncbi Structural investigations of the hemoglobin of the cyanobacterium Synechocystis PCC6803 reveal a unique distal heme pocket
    M Couture
    Department of Biochemistry and Microbiology, Laval University, Quebec, Canada
    Eur J Biochem 267:4770-80. 2000
  3. ncbi Assignment of the 1H, 13C, and 15N signals of Synechocystis sp. PCC 6803 methemoglobin
    Christopher J Falzone
    J Biomol NMR 23:71-2. 2002
  4. ncbi Novel histidine-heme covalent linkage in a hemoglobin
    B Christie Vu
    Department of Chemistry and the Center for Biomolecular Structure and Function, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Am Chem Soc 124:8544-5. 2002
  5. ncbi The solution structure of the recombinant hemoglobin from the cyanobacterium Synechocystis sp. PCC 6803 in its hemichrome state
    Christopher J Falzone
    Department of Chemistry and the Center for Biomolecular Structure and Function, The Pennsylvania State University, University Park, PA 16802, USA
    J Mol Biol 324:1015-29. 2002
  6. ncbi The crystal structure of Synechocystis hemoglobin with a covalent heme linkage
    Julie A Hoy
    Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA
    J Biol Chem 279:16535-42. 2004
  7. ncbi Crystallographic analysis of synechocystis cyanoglobin reveals the structural changes accompanying ligand binding in a hexacoordinate hemoglobin
    James T Trent
    Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50010, USA
    J Mol Biol 341:1097-108. 2004
  8. ncbi Structural and dynamic properties of Synechocystis sp. PCC 6803 Hb revealed by reconstitution with Zn-protoporphyrin IX
    Juliette T J Lecomte
    Department of Chemistry, The Pennsylvania State University, 104 Chemistry Building, University Park, PA 16802, USA
    J Inorg Biochem 99:1585-92. 2005
  9. ncbi Covalent heme attachment in Synechocystis hemoglobin is required to prevent ferrous heme dissociation
    Julie A Hoy
    Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, IA 50011, USA
    Protein Sci 16:250-60. 2007

Scientific Experts

  • JULIETTE T LECOMTE
  • Julie A Hoy
  • Christopher J Falzone
  • Mark S Hargrove
  • James T Trent
  • B Christie Vu
  • Suman Kundu
  • N L Scott
  • M Couture
  • Puspita Halder
  • Benoit J Smagghe
  • S Ramaswamy
  • Nancy L Scott
  • A Daniel Jones
  • P Y Savard
  • M Guertin
  • T K Das
  • D L Rousseau
  • J B Wittenberg
  • B A Wittenberg
  • Y Ouellet

Detail Information

Publications9

  1. ncbi Cloning, expression, purification, and preliminary characterization of a putative hemoglobin from the cyanobacterium Synechocystis sp. PCC 6803
    N L Scott
    Department of Chemistry and the Center for Biomolecular Structure and Function, The Pennsylvania State University, University Park 16802, USA
    Protein Sci 9:587-97. 2000
    The genome of the unicellular cyanobacterium Synechocystis sp. PCC 6803 contains a gene (slr2097, glbN) encoding a 123 amino-acid product with sequence similarity to globins...
  2. ncbi Structural investigations of the hemoglobin of the cyanobacterium Synechocystis PCC6803 reveal a unique distal heme pocket
    M Couture
    Department of Biochemistry and Microbiology, Laval University, Quebec, Canada
    Eur J Biochem 267:4770-80. 2000
    ..We conclude that the heme pocket of the wild type Synechocystis Hb has a unique structure that requires a histidine residue at the E10 position for the formation of its native structure...
  3. ncbi Assignment of the 1H, 13C, and 15N signals of Synechocystis sp. PCC 6803 methemoglobin
    Christopher J Falzone
    J Biomol NMR 23:71-2. 2002
  4. ncbi Novel histidine-heme covalent linkage in a hemoglobin
    B Christie Vu
    Department of Chemistry and the Center for Biomolecular Structure and Function, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Am Chem Soc 124:8544-5. 2002
    ..Dithionite treatment of the globin reconstituted with Zn protoporphyrin IX sample did not lead to 2-vinyl group modification, suggesting that the chemical reduction of the heme iron facilitated the attachment...
  5. ncbi The solution structure of the recombinant hemoglobin from the cyanobacterium Synechocystis sp. PCC 6803 in its hemichrome state
    Christopher J Falzone
    Department of Chemistry and the Center for Biomolecular Structure and Function, The Pennsylvania State University, University Park, PA 16802, USA
    J Mol Biol 324:1015-29. 2002
    ..Comparison to the truncated hemoglobin from the green alga Chlamydomonas eugametos also suggested how the endogenous hexacoordination affected the structure...
  6. ncbi The crystal structure of Synechocystis hemoglobin with a covalent heme linkage
    Julie A Hoy
    Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA
    J Biol Chem 279:16535-42. 2004
    ..The stereochemistry of hexacoordination is compared with other hexacoordinate hemoglobins and cytochromes in an effort to illuminate factors contributing to ligand affinity in hexacoordinate hemoglobins...
  7. ncbi Crystallographic analysis of synechocystis cyanoglobin reveals the structural changes accompanying ligand binding in a hexacoordinate hemoglobin
    James T Trent
    Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50010, USA
    J Mol Biol 341:1097-108. 2004
    ....
  8. ncbi Structural and dynamic properties of Synechocystis sp. PCC 6803 Hb revealed by reconstitution with Zn-protoporphyrin IX
    Juliette T J Lecomte
    Department of Chemistry, The Pennsylvania State University, 104 Chemistry Building, University Park, PA 16802, USA
    J Inorg Biochem 99:1585-92. 2005
    ..The NMR data also demonstrated that the H helix underwent complex dynamic processes near His117, a residue readily reacting with the wild-type heme 2-vinyl group in a post-translational modification...
  9. ncbi Covalent heme attachment in Synechocystis hemoglobin is required to prevent ferrous heme dissociation
    Julie A Hoy
    Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, IA 50011, USA
    Protein Sci 16:250-60. 2007
    ....