Gene Symbol: acpP
Description: acyl carrier protein
Alias: SC4A7.17
Species: Streptomyces coelicolor A3(2)

Top Publications

  1. Summers R, Ali A, Shen B, Wessel W, Hutchinson C. Malonyl-coenzyme A:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis. Biochemistry. 1995;34:9389-402 pubmed
    ..fatty acid synthase (FAS): the FabD malonyl-coenzyme A:ACP acyltransferase (MAT), FabH 3-oxoacyl:ACP synthase III, AcpP ACP, and FabB 3-oxoacyl:ACP synthase I. Expression of the S. glaucescens fabD gene in E...
  2. Schmoock G, Pfennig F, Jewiarz J, Schlumbohm W, Laubinger W, Schauwecker F, et al. Functional cross-talk between fatty acid synthesis and nonribosomal peptide synthesis in quinoxaline antibiotic-producing streptomycetes. J Biol Chem. 2005;280:4339-49 pubmed publisher
    ..These data show for the first time a functional interaction between nonribosomal peptide synthesis and fatty acid synthesis...
  3. Watanabe K, Hotta K, Praseuth A, Koketsu K, Migita A, Boddy C, et al. Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli. Nat Chem Biol. 2006;2:423-8 pubmed publisher
  4. Revill W, Bibb M, Hopwood D. Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant. J Bacteriol. 1995;177:3946-52 pubmed
    ..coelicolor. Disruption of the operon containing the malonyltransferase gene proved to be impossible, supporting the idea that the malonyltransferase plays an essential role in fatty acid biosynthesis...
  5. Revill W, Bibb M, Hopwood D. Relationships between fatty acid and polyketide synthases from Streptomyces coelicolor A3(2): characterization of the fatty acid synthase acyl carrier protein. J Bacteriol. 1996;178:5660-7 pubmed
    ..The corresponding gene (acpP) was cloned and sequenced and found to lie within 1 kb of a previously characterized gene (fabD) encoding another ..