Gene Symbol: rmlB
Description: dTDP-glucose-4,6-dehydratase
Alias: SMU.1457
Species: Streptococcus mutans UA159

Top Publications

  1. Yoshida Y, Ganguly S, Bush C, Cisar J. Molecular basis of L-rhamnose branch formation in streptococcal coaggregation receptor polysaccharides. J Bacteriol. 2006;188:4125-30 pubmed publisher
    ..gordonii 38 and wefH in S. oralis 34. These genes were distinguished by the unique ability of WefC to act on the branched acceptor formed by the action of WefB...
  2. Morona J, Morona R, Paton J. Analysis of the 5' portion of the type 19A capsule locus identifies two classes of cpsC, cpsD, and cpsE genes in Streptococcus pneumoniae. J Bacteriol. 1999;181:3599-605 pubmed
    ..Whereas members within one class are greater than 95% identical to each other, the DNA sequence identity between the two classes is only approximately 70%...
  3. Allard S, Beis K, Giraud M, Hegeman A, Gross J, Wilmouth R, et al. Toward a structural understanding of the dehydratase mechanism. Structure. 2002;10:81-92 pubmed
    dTDP-D-glucose 4,6-dehydratase (RmlB) was first identified in the L-rhamnose biosynthetic pathway, where it catalyzes the conversion of dTDP-D-glucose into dTDP-4-keto-6-deoxy-D-glucose...
  4. Yoshida Y, Ganguly S, Bush C, Cisar J. Carbohydrate engineering of the recognition motifs in streptococcal co-aggregation receptor polysaccharides. Mol Microbiol. 2005;58:244-56 pubmed publisher
    ..The reactions of these genetically modified polysaccharides as antigens and receptors provide further insight into the structural basis of RPS function...
  5. Morona J, Morona R, Paton J. Characterization of the locus encoding the Streptococcus pneumoniae type 19F capsular polysaccharide biosynthetic pathway. Mol Microbiol. 1997;23:751-63 pubmed
    ..pneumoniae serotypes/groups tested. The region from cps19fG to cps19fK was found only in members of serogroup 19, and, within this, cps19fl was unique to type 19F...
  6. Morona J, Morona R, Paton J. Comparative genetics of capsular polysaccharide biosynthesis in Streptococcus pneumoniae types belonging to serogroup 19. J Bacteriol. 1999;181:5355-64 pubmed