Gene Symbol: vgaA
Description: ABC protein
Alias: ABC protein, VgaA
Species: Staphylococcus aureus

Top Publications

  1. Gentry D, McCloskey L, Gwynn M, Rittenhouse S, Scangarella N, Shawar R, et al. Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. Antimicrob Agents Chemother. 2008;52:4507-9 pubmed publisher
    ..aureus recent clinical isolates evaluated. The ABC proteins VgaAv and VgaA were found to be responsible for the reduced susceptibility to pleuromutilins exhibited by these six isolates.
  2. Qin X, Poon B, Kwong J, Niles D, Schmidt B, Rajagopal L, et al. Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. Int J Antimicrob Agents. 2011;38:81-3 pubmed publisher
    ..aureus. The native plasmids carrying vga(A)(LC) were transferable to a susceptible laboratory strain of S. aureus in vitro, in which they conferred resistance patterns similar to the parent isolates...