Gene Symbol: cspA
Description: RNA chaperone/anti-terminator
Species: Shigella flexneri 2a str. 301

Top Publications

  1. Goldstein J, Pollitt N, Inouye M. Major cold shock protein of Escherichia coli. Proc Natl Acad Sci U S A. 1990;87:283-7 pubmed
    ..We have cloned the gene encoding this protein and have completed the nucleotide sequence analysis, which revealed that the gene encodes a hydrophilic protein of 70 amino acid residues...
  2. Feng W, Tejero R, Zimmerman D, Inouye M, Montelione G. Solution NMR structure and backbone dynamics of the major cold-shock protein (CspA) from Escherichia coli: evidence for conformational dynamics in the single-stranded RNA-binding site. Biochemistry. 1998;37:10881-96 pubmed publisher
    The major cold-shock protein (CspA) from Escherichia coli is a single-stranded nucleic acid-binding protein that is produced in response to cold stress...
  3. Newkirk K, Feng W, Jiang W, Tejero R, Emerson S, Inouye M, et al. Solution NMR structure of the major cold shock protein (CspA) from Escherichia coli: identification of a binding epitope for DNA. Proc Natl Acad Sci U S A. 1994;91:5114-8 pubmed
    Sequence-specific 1H and 15N resonance assignments have been determined for the major cold shock protein (CspA) from Escherichia coli with recently developed three-dimensional triple-resonance NMR experiments...
  4. Francis K, Stewart G. Detection and speciation of bacteria through PCR using universal major cold-shock protein primer oligomers. J Ind Microbiol Biotechnol. 1997;19:286-93 pubmed
    ..Sequence analysis of the amplified products confirmed a high level of DNA homology. Significantly, however, there are sufficient nucleotide variations to allow the unique allocation of each amplified sequence to its parental bacterium...