MMP13

Summary

Gene Symbol: MMP13
Description: matrix metallopeptidase 13
Alias: MMP-13, collagenase 3, matrix metallopeptidase 13 (collagenase 3)
Species: sheep

Top Publications

  1. Lo I, Marchuk L, Majima T, Frank C, Hart D. Medial collateral ligament and partial anterior cruciate ligament transection: mRNA changes in uninjured ligaments of the sheep knee. J Orthop Sci. 2003;8:707-13 pubmed
    ..These responses may be an adaptive attempt to preserve function until the scar tissue can stabilize the mechanical environment following injury. ..
  2. Ricke W, Smith G, Smith M. Matrix metalloproteinase expression and activity following prostaglandin F(2 alpha)-induced luteolysis. Biol Reprod. 2002;66:685-91 pubmed
    ..MMP mRNA expression and activity were significantly increased following PGF(2 alpha) treatment. Increased MMP activity may promote ECM degradation during luteolysis. ..
  3. Jackson M, Smith M, Smith S, Jackson C, Xue M, Little C. Activation of cartilage matrix metalloproteinases by activated protein C. Arthritis Rheum. 2009;60:780-91 pubmed publisher
    ..APC could not directly activate proMMP-13, but it was associated with increased MMP-2 and MMP-9 activity. APC may be a relevant activator of MMPs in cartilage and may play a role in progressive cartilage degradation in arthritis...