Research Topics
Genomes and Genes
| LOC443410SummaryGene Symbol: LOC443410 Description: H(+)-transporting ATP synthase Species: sheep Publications The sequence of the major protein stored in ovine ceroid lipofuscinosis is identical with that of the dicyclohexylcarbodiimide-reactive proteolipid of mitochondrial ATP synthaseI M Fearnley M R C Laboratory of Molecular Biology, Cambridge Biochem J 268:751-8 Ovine ceroid lipofuscinosis. The major lipopigment protein and the lipid-binding subunit of mitochondrial ATP synthase have the same NH2-terminal sequenceD N Palmer Department of Veterinary Pathology and Public Health Massey University, Palmerston North, New Zealand J Biol Chem 264:5736-40 Characterization of the expressed genes for subunit c of mitochondrial ATP synthase in sheep with ceroid lipofuscinosisS M Medd ol>Medical Research Council Laboratory of Molecular Biology, Cambridge Biochem J 293:65-73 |
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Publications
The sequence of the major protein stored in ovine ceroid lipofuscinosis is identical with that of the dicyclohexylcarbodiimide-reactive proteolipid of mitochondrial ATP synthaseI M Fearnley
M R C Laboratory of Molecular Biology, Cambridge
Biochem J 268:751-8
M R C Laboratory of Molecular Biology, Cambridge
Biochem J 268:751-8
....
Ovine ceroid lipofuscinosis. The major lipopigment protein and the lipid-binding subunit of mitochondrial ATP synthase have the same NH2-terminal sequenceD N Palmer
Department of Veterinary Pathology and Public Health Massey University, Palmerston North, New Zealand
J Biol Chem 264:5736-40
Department of Veterinary Pathology and Public Health Massey University, Palmerston North, New Zealand
J Biol Chem 264:5736-40
..e. the disease is a proteolipid proteinosis, specifically a lysosomal mitochondrial ATP synthase lipid-binding subunit proteinosis. The analogous human diseases are likely to reflect storage of the same or similar peptides...
Characterization of the expressed genes for subunit c of mitochondrial ATP synthase in sheep with ceroid lipofuscinosisS M Medd
Medical Research Council Laboratory of Molecular Biology, Cambridge
Biochem J 293:65-73
Medical Research Council Laboratory of Molecular Biology, Cambridge
Biochem J 293:65-73
..However, restriction fragment analysis of genomic DNA from a further 12 sheep established that the sequence differences were not linked to ceroid lipofuscinosis...
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