HYAL2

Summary

Gene Symbol: HYAL2
Description: hyaluronoglucosaminidase 2
Alias: oHyal2, GPI-anchored surface protein, Hyal2 protein, JSRV envelope protein receptor, hyal-2, hyaluronidase-2, hyaluronoglucosaminidase-2
Species: sheep

Publications

  1. Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation
    S K Rai
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Proc Natl Acad Sci U S A 98:4443-8
  2. Mechanism of cell entry and transformation by enzootic nasal tumor virus
    Clarissa Dirks
    Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109, USA
    J Virol 76:2141-9

Detail Information

Publications2

  1. Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation
    S K Rai
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Proc Natl Acad Sci U S A 98:4443-8
    ..used phenotypic screening of radiation hybrid cell lines to identify the candidate lung cancer tumor suppressor HYAL2/LUCA2 as the receptor for JSRV...
  2. Mechanism of cell entry and transformation by enzootic nasal tumor virus
    Clarissa Dirks
    Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109, USA
    J Virol 76:2141-9
    ..the ENTV Env protein mediates virus entry using the same receptor as does JSRV Env, the candidate tumor suppressor Hyal2. However, ENTV Env mediates entry into cells from a more restricted range of species than does JSRV, and based on ..