DCN

Summary

Gene Symbol: DCN
Description: decorin
Alias: decorin, PG-S2, PG40, bone proteoglycan II
Species: sheep

Top Publications

  1. Little C, Ghosh P, Bellenger C. Topographic variation in biglycan and decorin synthesis by articular cartilage in the early stages of osteoarthritis: an experimental study in sheep. J Orthop Res. 1996;14:433-44 pubmed
    ..with hyaluronic acid (aggrecan) and small species, particularly biglycan (dermatan sulphate proteoglycan-1) and decorin (dermatan sulphate proteoglycan-2), that do not...
  2. Melrose J, Ghosh P, Taylor T, Vernon Roberts B, Latham J, Moore R. Elevated synthesis of biglycan and decorin in an ovine annular lesion model of experimental disc degeneration. Eur Spine J. 1997;6:376-84 pubmed
    ..after induction of the annular lesion, AF cells isolated from the lesion produced significantly higher levels of decorin and biglycan in alginate bead culture than did cells from equivalent zones of the controls...
  3. Wu W, Zhang Q, Unno N, Derks J, Nathanielsz P. Characterization of decorin mRNA in pregnant intrauterine tissues of the ewe and regulation by steroids. Am J Physiol Cell Physiol. 2000;278:C199-206 pubmed
    In this study, we characterized the changes in the extracellular matrix proteoglycan decorin in pregnant intrauterine tissues in late gestation and in association with labor and delivery in sheep...
  4. Melrose J, Ghosh P, Taylor T. A comparative analysis of the differential spatial and temporal distributions of the large (aggrecan, versican) and small (decorin, biglycan, fibromodulin) proteoglycans of the intervertebral disc. J Anat. 2001;198:3-15 pubmed
    ..The main small PG detectable in the fetal discs was biglycan, whereas decorin predominated in the 2 and 10 y old IVD samples; its levels were highest in the outer annulus fibrosus (AF)...