Gene Symbol: F
Description: fusion protein
Species: Sendai virus
Itoh M, Isegawa Y, Hotta H, Homma M. Isolation of an avirulent mutant of Sendai virus with two amino acid mutations from a highly virulent field strain through adaptation to LLC-MK2 cells. J Gen Virol. 1997;78 ( Pt 12):3207-15 pubmed publisher
Suzuki H, Kurooka M, Hiroaki Y, Fujiyoshi Y, Kaneda Y. Sendai virus F glycoprotein induces IL-6 production in dendritic cells in a fusion-independent manner. FEBS Lett. 2008;582:1325-9 pubmed publisher
..Reconstituted liposomes containing F protein stimulated IL-6 production. The antibody against F protein inhibited IL-6 secretion by HVJ-E...
Bampi C, Rasga L, Roux L. Antagonism to human BST-2/tetherin by Sendai virus glycoproteins. J Gen Virol. 2013;94:1211-9 pubmed publisher
..Suppression of the virus envelope proteins matrix, fusion (F) or haemagglutinin-neuraminidase protein (HN) during the course of infection demonstrates that F and HN, in concert, ..
Shevtsova Horoz A, Essaidi Laziosi M, Roux L. Sendai virus particle production: a more detailed role of F and HN through, namely, their association with M. Virus Res. 2015;199:31-41 pubmed publisher
The Paramyxovirus membrane associated proteins are composed of two integral membrane glycoproteins, HN (H, G) and F, and of a matrix protein (M) carpeting the membrane inner layer...
Wang X, Xu Y, Cole D, Lou Z, Liu Y, Rao Z, et al
. Biochemical, biophysical and preliminary X-ray crystallographic analyses of the fusion core of Sendai virus F protein. Acta Crystallogr D Biol Crystallogr. 2004;60:1632-5 pubmed
..HN (or its homologue H or G) binds a cellular receptor which triggers conformational changes of its fusion protein, F. There are at least three conformations of the F protein in the current fusion model: the pre-fusion native ..
Luque L, Bridges O, Mason J, Boyd K, Portner A, Russell C. Residues in the heptad repeat a region of the fusion protein modulate the virulence of Sendai virus in mice. J Virol. 2010;84:810-21 pubmed publisher
While the molecular basis of fusion (F) protein refolding during membrane fusion has been studied extensively in vitro, little is known about the biological significance of membrane fusion activity in parainfluenza virus replication and ..