Gene Symbol: C
Description: C' protein
Species: Sendai virus
Itoh M, Isegawa Y, Hotta H, Homma M. Isolation of an avirulent mutant of Sendai virus with two amino acid mutations from a highly virulent field strain through adaptation to LLC-MK2 cells. J Gen Virol. 1997;78 ( Pt 12):3207-15 pubmed publisher
..the attenuation of mouse pathogenicity of MVC11 were associated with only two amino acid substitutions; one on the C protein (Phe substituted by Ser at position 170) and the other on the RNA polymerase, the L protein (Glu substituted ..
de Breyne S, Stalder R, Curran J. Intracellular processing of the Sendai virus C' protein leads to the generation of a Y protein module: structure-functional implications. FEBS Lett. 2005;579:5685-90 pubmed publisher
..This core was conserved in the C protein. We propose that C' functions as a Pro-protein delivering the Y module to a specific intracellular location.