Gene Symbol: a2m
Description: alpha-2-macroglobulin homologue
Alias: CD109, alpha-2-macroglobulin homologue
Species: sea vase

Top Publications

  1. Nonaka M, Yoshizaki F. Evolution of the complement system. Mol Immunol. 2004;40:897-902 pubmed
    ..Thus, the vertebrate complement system seems to be established by integrating some independent parts into one reaction system...
  2. Hammond J, Nakao M, Smith V. Cloning of a glycosylphosphatidylinositol-anchored alpha-2-macroglobulin cDNA from the ascidian, Ciona intestinalis, and its possible role in immunity. Mol Immunol. 2005;42:683-94 pubmed
    ..Its tissue distribution coupled with its sequence characteristics and unusual domain structure indicate that the encoded protein probably assists in host defence by entrapping and inhibiting proteases from micro-organisms. ..