Gene Symbol: iroC
Description: multidrug ABC transporter ATP-binding protein
Species: Salmonella typhimurium LT2

Top Publications

  1. Wu W, Hsieh P, Huang T, Chang Y, Chang C. Cloning and characterization of an iron regulated locus, iroA, in Salmonella enterica serovar Choleraesuis. DNA Seq. 2002;13:333-41 pubmed
    ..enterica serovar Choleraesuis by allelic exchange resulted in the loss of expression of the 78 kDa protein. However, this mutant had a similar LD50 to mice compared to the parent strain when given intraperitoneally. ..
  2. Crouch M, Castor M, Karlinsey J, Kalhorn T, Fang F. Biosynthesis and IroC-dependent export of the siderophore salmochelin are essential for virulence of Salmonella enterica serovar Typhimurium. Mol Microbiol. 2008;67:971-83 pubmed publisher
    ..that the Major Facilitator Superfamily pump EntS is the major exporter of enterobactin and the ABC transporter IroC exports both salmochelin and enterobactin...