Gene Symbol: fis
Description: Fis family transcriptional regulator
Species: Salmonella typhimurium LT2

Top Publications

  1. Osuna R, Lienau D, Hughes K, Johnson R. Sequence, regulation, and functions of fis in Salmonella typhimurium. J Bacteriol. 1995;177:2021-32 pubmed
    The fis operon from Salmonella typhimurium has been cloned and sequenced, and the properties of Fis-deficient and Fis-constitutive strains were examined. The overall fis operon organization in S...
  2. O Cr in n T, Carroll R, Kelly A, Dorman C. Roles for DNA supercoiling and the Fis protein in modulating expression of virulence genes during intracellular growth of Salmonella enterica serovar Typhimurium. Mol Microbiol. 2006;62:869-82 pubmed publisher
    ..This enhancement of expression also required the Fis nucleoid-associated protein...
  3. O Cr in n T, Dorman C. Expression of the Fis protein is sustained in late-exponential- and stationary-phase cultures of Salmonella enterica serovar Typhimurium grown in the absence of aeration. Mol Microbiol. 2007;66:237-51 pubmed publisher
    The classic expression pattern of the Fis global regulatory protein during batch culture consists of a high peak in the early logarithmic phase of growth, followed by a sharp decrease through mid-exponential growth phase until Fis is ..
  4. Wang H, Liu B, Wang Q, Wang L. Genome-wide analysis of the salmonella Fis regulon and its regulatory mechanism on pathogenicity islands. PLoS ONE. 2013;8:e64688 pubmed publisher
    b>Fis, one of the most important nucleoid-associated proteins, functions as a global regulator of transcription in bacteria that has been comprehensively studied in Escherichia coli K12...
  5. McLean M, Chang Y, Dhar G, Heiss J, Johnson R. Multiple interfaces between a serine recombinase and an enhancer control site-specific DNA inversion. elife. 2013;2:e01211 pubmed publisher
    ..that are regulated by a remote recombinational enhancer element containing two binding sites for the protein Fis. Two Hin dimers bound to specific recombination sites associate with the Fis-bound enhancer by DNA looping where ..
  6. Wang H, Wang L, Li P, Hu Y, Zhang W, Tang B. Dynamic Transcriptional Regulation of Fis in Salmonella During the Exponential Phase. Curr Microbiol. 2015;71:713-8 pubmed publisher
    b>Fis is one of the most important global regulators and has attracted extensive research attention...
  7. Hirsch M, Elliott T. Fis regulates transcriptional induction of RpoS in Salmonella enterica. J Bacteriol. 2005;187:1568-80 pubmed publisher
    ..enterica serovar Typhimurium and report that regulation of transcription during growth into SP depends on Fis, a DNA-binding protein whose abundance is high during exponential growth and very low in SP. A fis mutant of S...