Gene Symbol: csrA
Description: carbon storage regulator
Species: Salmonella typhimurium LT2
Kerrinnes T, Zelas Z, Streckel W, Faber F, Tietze E, Tschäpe H, et al
. CsrA and CsrB are required for the post-transcriptional control of the virulence-associated effector protein AvrA of Salmonella enterica. Int J Med Microbiol. 2009;299:333-41 pubmed publisher
..of copy-dependent, post-transcriptional control of AvrA was shown to be dependent on the regulatory action of the CsrA/CsrB system since the deletion of both genes completely abolished the translation in the tested S...
Altier C, Suyemoto M, Lawhon S. Regulation of Salmonella enterica serovar typhimurium invasion genes by csrA. Infect Immun. 2000;68:6790-7 pubmed
..We report here that epithelial cell invasion requires the serovar Typhimurium homologue of Escherichia coli csrA, which encodes a regulator that alters the stability of specific mRNA targets...
Knudsen G, Olsen J, Aabo S, Barrow P, Rychlik I, Thomsen L. ClpP deletion causes attenuation of Salmonella Typhimurium virulence through mis-regulation of RpoS and indirect control of CsrA and the SPI genes. Microbiology. 2013;159:1497-509 pubmed publisher
..including the proteolytic component ClpP, the stationary phase regulator RpoS and the carbon-storage regulator CsrA. However, the mechanism behind the ClpP regulation is not fully understood...
Knudsen G, Nielsen M, Thomsen L, Aabo S, Rychlik I, Olsen J. The role of ClpP, RpoS and CsrA in growth and filament formation of Salmonella enterica serovar Typhimurium at low temperature. BMC Microbiol. 2014;14:208 pubmed publisher
..In the current study, we evaluated the importance of the Clp proteolytic complex and the carbon starvation protein, CsrA, for the ability of Salmonella Typhimurium to grow at low temperature...
Holmqvist E, Wright P, Li L, Bischler T, Barquist L, Reinhardt R, et al
. Global RNA recognition patterns of post-transcriptional regulators Hfq and CsrA revealed by UV crosslinking in vivo. EMBO J. 2016;35:991-1011 pubmed publisher
..have applied CLIP-seq to chart the target landscape of two major bacterial post-transcriptional regulators, Hfq and CsrA, in the model pathogen Salmonella Typhimurium...
Mart nez L, Yakhnin H, Camacho M, Georgellis D, Babitzke P, Puente J, et al
. Integration of a complex regulatory cascade involving the SirA/BarA and Csr global regulatory systems that controls expression of the Salmonella SPI-1 and SPI-2 virulence regulons through HilD. Mol Microbiol. 2011;80:1637-56 pubmed publisher
..In this study, we demonstrate that CsrA, a global regulatory RNA binding protein, post-transcriptionally regulates hilD expression by directly binding near ..