Gene Symbol: YHR020W
Description: proline--tRNA ligase
Alias: proline--tRNA ligase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Tatusov R, Galperin M, Natale D, Koonin E. The COG database: a tool for genome-scale analysis of protein functions and evolution. Nucleic Acids Res. 2000;28:33-6 pubmed
    ..The COG database is accompanied by the COGNITOR program that is used to fit new proteins into the COGs and can be applied to functional and phylogenetic annotation of newly sequenced genomes. ..
  2. Sternjohn J, Hati S, Siliciano P, Musier Forsyth K. Restoring species-specific posttransfer editing activity to a synthetase with a defunct editing domain. Proc Natl Acad Sci U S A. 2007;104:2127-32 pubmed
    ..In this manner, a single editing module can be distributed to different synthetases, and simultaneously acquire specificity and enhanced activity. ..
  3. Hati S, Ziervogel B, Sternjohn J, Wong F, Nagan M, Rosen A, et al. Pre-transfer editing by class II prolyl-tRNA synthetase: role of aminoacylation active site in "selective release" of noncognate amino acids. J Biol Chem. 2006;281:27862-72 pubmed
  4. Ben Aroya S, Coombes C, Kwok T, O Donnell K, Boeke J, Hieter P. Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Mol Cell. 2008;30:248-58 pubmed publisher
    ..The importance of this collection is demonstrated by biochemical and genetic screens that reveal essential genes involved in RNA processing and maintenance of chromosomal stability. ..