Gene Symbol: YAP7
Species: Saccharomyces cerevisiae S288c
Fernandes L, Rodrigues Pousada C, Struhl K. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol Cell Biol. 1997;17:6982-93 pubmed
..Thus, members of the Yap family carry out overlapping but distinct biological functions. ..
Munoz I, Simon E, Casals N, Clotet J, Arino J. Identification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae. Yeast. 2003;20:157-69 pubmed
..The possible relationship between the known functions of these suppressor genes and the progress through the G(1)-S transition is discussed. ..
Stirling P, Srayko M, Takhar K, Pozniakovsky A, Hyman A, Leroux M. Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression. Mol Biol Cell. 2007;18:2336-45 pubmed
..Our data support a model in which Plp2p modulates the biogenesis of several CCT substrates relating to cell cycle and cytoskeletal function, which together contribute to the essential function of PLP2. ..
Aucher W, Becker E, Ma E, Miron S, Martel A, Ochsenbein F, et al
. A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic data. Mol Cell Proteomics. 2010;9:2745-59 pubmed publisher
..The STRIP method relies on a combination of conservation, phosphorylation likelihood, and binding specificity criteria and can be accessed via a web interface at http://biodev.extra.cea.fr/strip/. ..
Merhej J, Delaveau T, Guitard J, Palancade B, Hennequin C, Garcia M, et al
. Yap7 is a transcriptional repressor of nitric oxide oxidase in yeasts, which arose from neofunctionalization after whole genome duplication. Mol Microbiol. 2015;96:951-72 pubmed publisher
..in the model yeast Saccharomyces cerevisiae and in the human pathogen Candida glabrata, the transcription factor Yap7 constitutively represses YHB1 by binding its promoter...
Fordyce P, Gerber D, Tran D, Zheng J, Li H, Derisi J, et al
. De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis. Nat Biotechnol. 2010;28:970-5 pubmed publisher
..We expect that these data and future use of this technique will provide information essential for understanding transcription factor specificity, improving identification of regulatory sites and reconstructing regulatory interactions. ..