Gene Symbol: YAP6
Alias: HAL7, Yap6p
Species: Saccharomyces cerevisiae S288c
Fernandes L, Rodrigues Pousada C, Struhl K. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol Cell Biol. 1997;17:6982-93 pubmed
..Thus, members of the Yap family carry out overlapping but distinct biological functions. ..
Furuchi T, Ishikawa H, Miura N, Ishizuka M, Kajiya K, Kuge S, et al
. Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae. Mol Pharmacol. 2001;59:470-4 pubmed
..These two nuclear proteins might act as transcriptional factors, regulating the expression of certain genes that confer resistance to DNA-alkylating agents. ..
Tan K, Feizi H, Luo C, Fan S, Ravasi T, IDEKER T. A systems approach to delineate functions of paralogous transcription factors: role of the Yap family in the DNA damage response. Proc Natl Acad Sci U S A. 2008;105:2934-9 pubmed publisher
..The data further highlight differences among Yap paralogs in terms of their regulatory mode of action (activation vs. repression). This study suggests how other large TF families might be disentangled in the future. ..
Hanlon S, Rizzo J, Tatomer D, Lieb J, Buck M. The stress response factors Yap6, Cin5, Phd1, and Skn7 direct targeting of the conserved co-repressor Tup1-Ssn6 in S. cerevisiae. PLoS ONE. 2011;6:e19060 pubmed publisher
..Four top candidates, Cin5, Skn7, Phd1, and Yap6, all known to be associated with stress response gene regulation, were experimentally confirmed to physically ..
Bastajian N, Friesen H, Andrews B. Bck2 acts through the MADS box protein Mcm1 to activate cell-cycle-regulated genes in budding yeast. PLoS Genet. 2013;9:e1003507 pubmed publisher
..Our data suggest that Yox1 and Bck2 may compete for access to the Mcm1-ECB scaffold to ensure appropriate activation of the initial suite of genes required for cell cycle commitment. ..
Jackson T, Kwon E, Chachulska A, Hyman L. Novel roles for elongin C in yeast. Biochim Biophys Acta. 2000;1491:161-76 pubmed
..This suggests a novel role for Elongin C and provides insights into additional potential functions in mammalian cells. ..
Mak H, Pillus L, Ideker T. Dynamic reprogramming of transcription factors to and from the subtelomere. Genome Res. 2009;19:1014-25 pubmed publisher
..Taken together, these results underscore the importance of genome structure in understanding the regulatory dynamics of transcriptional networks. ..
Biver S, Portetelle D, Vandenbol M. Multicopy suppression screen in a Saccharomyces cerevisiae strain lacking the Rab GTPase-activating protein Msb3p. Biotechnol Lett. 2011;33:123-9 pubmed publisher
..genes (ADH1, RNT1, and SUI1) were found to suppress the CdCl(2) sensitivity of the msb3 strain and three others (YAP6, ZEO1, and SLM1) its diltiazem-HCl sensitivity...