Genomes and Genes
Gene Symbol: VAR1
Description: mitochondrial 37S ribosomal protein VAR1
Alias: mitochondrial 37S ribosomal protein VAR1
Species: Saccharomyces cerevisiae S288c
- Zassenhaus H, Perlman P. Respiration deficient mutants in the A+T-rich region on yeast mitochondrial DNA containing the var1 gene. Curr Genet. 1982;6:179-88 pubmed publisherSeveral mit mutants mapping within or near the var1 determinant region have been characterized genetically and biochemically...
- Davis S, Ellis S. Incorporation of the yeast mitochondrial ribosomal protein Mrp2 into ribosomal subunits requires the mitochondrially encoded Var1 protein. Mol Gen Genet. 1995;247:379-86 pubmed..The mitochondrial genome of S. cerevisiae encodes two components of the small ribosomal subunit, 15S rRNA and the Var1 protein, both of which are necessary for the formation of mature 37S subunits...
- Herrmann J, Stuart R, Craig E, Neupert W. Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA. J Cell Biol. 1994;127:893-902 pubmed..In particular, we show that mt-Hsp70 acts in maintaining the var1 protein, the only mitochondrially encoded subunit of mitochondrial ribosomes, in an assembly competent state, ..
- Fontanesi F, SOTO I, Horn D, Barrientos A. Mss51 and Ssc1 facilitate translational regulation of cytochrome c oxidase biogenesis. Mol Cell Biol. 2010;30:245-59 pubmed publisher..We conclude that Ssc1, by interacting with Mss51 and Mss51-containing complexes, plays a critical role in Cox1 biogenesis, COX assembly, and the translational regulation of these processes. ..