Gene Symbol: UTP10
Description: snoRNA-binding rRNA-processing protein UTP10
Alias: snoRNA-binding rRNA-processing protein UTP10
Species: Saccharomyces cerevisiae S288c
Pérez Fernández J, Roman A, De Las Rivas J, Bustelo X, Dosil M. The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol. 2007;27:5414-29 pubmed
..Together, our data identify the mechanism of assembly of the 90S preribosome and offer novel information about its internal architecture. ..
Dez C, Dlakic M, Tollervey D. Roles of the HEAT repeat proteins Utp10 and Utp20 in 40S ribosome maturation. RNA. 2007;13:1516-27 pubmed
..We report the detailed characterization of two of these factors, Utp10 and Utp20, which were initially identified as components of the small subunit processome...
Gallagher J, Dunbar D, Granneman S, Mitchell B, Osheim Y, Beyer A, et al
. RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes Dev. 2004;18:2506-17 pubmed
..This association may thus represent an early step in the formation of the SSU processome. Our results indicate that rRNA transcription and pre-rRNA processing are coordinated via specific components of the SSU processome. ..
Hoang T, Peng W, Vanrobays E, Krogan N, Hiley S, Beyer A, et al
. Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. Mol Cell Biol. 2005;25:5523-34 pubmed
..The identification of ABT1 in a large-scale analysis of the human nucleolar proteome indicates that its role may also be conserved in mammals. ..
Freed E, Baserga S. The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis. Nucleic Acids Res. 2010;38:4798-806 pubmed publisher
..Furthermore, these results allow us to propose that NAIC may be caused by dysfunctional pre-ribosome assembly due to the loss of an interaction between the C-terminus of Utp4/Cirhin and another SSU processome protein. ..
Moriggi G, Nieto B, Dosil M. Rrp12 and the Exportin Crm1 participate in late assembly events in the nucleolus during 40S ribosomal subunit biogenesis. PLoS Genet. 2014;10:e1004836 pubmed publisher
Bernstein K, Granneman S, Lee A, Manickam S, Baserga S. Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis. Mol Cell Biol. 2006;26:1195-208 pubmed
..In addition, we found that yeasts disrupted in expression of the two nonessential RNA helicases, Dbp3 and Dbp7, grew worse than when either one alone was disrupted. ..
Subba Rao G, Bachhawat A, Gupta C. Two-hybrid-based analysis of protein-protein interactions of the yeast multidrug resistance protein, Pdr5p. Funct Integr Genomics. 2002;1:357-66 pubmed
..The possibility of an interaction between the CL1 loops of two neighboring Pdr5p molecules was also indicated, which could possibly have implications for dimerization of this protein...