SFC1

Summary

Gene Symbol: SFC1
Description: Sfc1p
Alias: ACR1, Sfc1p
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Palmieri L, Lasorsa F, De Palma A, Palmieri F, Runswick M, Walker J. Identification of the yeast ACR1 gene product as a succinate-fumarate transporter essential for growth on ethanol or acetate. FEBS Lett. 1997;417:114-8 pubmed
    The protein encoded by the ACR1 gene in Saccharomyces cerevisiae belongs to a family of 35 related membrane proteins that are encoded in the fungal genome...
  2. Lin A, Anderson S, Minard K, McAlister Henn L. Effects of excess succinate and retrograde control of metabolite accumulation in yeast tricarboxylic cycle mutants. J Biol Chem. 2011;286:33737-46 pubmed publisher
    ..Co-disruption of the SFC1 gene encoding the mitochondrial succinate/fumarate transporter resulted in higher relative mitochondrial levels of ..
  3. Fernandez M, Fernandez E, Rodicio R. ACR1, a gene encoding a protein related to mitochondrial carriers, is essential for acetyl-CoA synthetase activity in Saccharomyces cerevisiae. Mol Gen Genet. 1994;242:727-35 pubmed
    ..We have isolated a mutant, termed acr1, defective for this activity by screening for mutants unable to utilize ethanol as a sole carbon source...
  4. Lauffer S, Mäbert K, Czupalla C, Pursche T, Hoflack B, Rödel G, et al. Saccharomyces cerevisiae porin pore forms complexes with mitochondrial outer membrane proteins Om14p and Om45p. J Biol Chem. 2012;287:17447-58 pubmed publisher
    ..We propose a model for the role of the two OM proteins in addressing the porin pore to bind to specific channels in the mt IM to facilitate transport of metabolites. ..