RPS8A

Summary

Gene Symbol: RPS8A
Description: ribosomal 40S subunit protein S8A
Alias: ribosomal 40S subunit protein S8A
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Zhou W, Ryan J, Zhou H. Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses. J Biol Chem. 2004;279:32262-8 pubmed
    ..Taken together, these results show that protein sumoylation is broadly involved in many cellular functions and this mass spectrometry-based proteomic approach is useful in studying the regulation of protein sumoylation in the cells. ..
  2. Kispal G, Sipos K, Lange H, Fekete Z, Bedekovics T, Janaky T, et al. Biogenesis of cytosolic ribosomes requires the essential iron-sulphur protein Rli1p and mitochondria. EMBO J. 2005;24:589-98 pubmed
    ..Thus, ribosome biogenesis and function are intimately linked to the crucial role of mitochondria in the maturation of the essential Fe/S protein Rli1p...
  3. Gromadka R, Karkusiewicz I, Rempoła B, Rytka J. Functional and physical interactions of Krr1p, a Saccharomyces cerevisiae nucleolar protein. Acta Biochim Pol. 2004;51:173-87 pubmed
    ..Thus, Krr1p and the genes encoding ribosomal proteins it interacts with seem to be coordinately regulated at the level of transcription. ..
  4. Pech M, Spreter T, Beckmann R, Beatrix B. Dual binding mode of the nascent polypeptide-associated complex reveals a novel universal adapter site on the ribosome. J Biol Chem. 2010;285:19679-87 pubmed publisher
    ..In addition to the previously identified universal adapter site represented by Rpl25/Rpl35, we therefore refer to Rpl31/Rpl17 as a novel universal docking site for ribosome-associated factors on the eukaryotic ribosome. ..
  5. Reineke L, Cao Y, Baus D, Hossain N, Merrick W. Insights into the role of yeast eIF2A in IRES-mediated translation. PLoS ONE. 2011;6:e24492 pubmed publisher
    ..These data suggest that eIF2A acts as a switch to regulate IRES-mediated translation, and eEF1A may be an important mediator of translational activation during ethanol stress. ..
  6. Otaka E, Higo K, Itoh T. Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes. Mol Gen Genet. 1984;195:544-6 pubmed
    ..Comparison of the amino-terminal sequences with all other ribosomal protein sequences so far available indicates that YS9 shows sequence homology to rat liver ribosomal protein S8 (Wittmann-Liebold et al. 1979). ..
  7. Denison C, Rudner A, Gerber S, Bakalarski C, Moazed D, Gygi S. A proteomic strategy for gaining insights into protein sumoylation in yeast. Mol Cell Proteomics. 2005;4:246-54 pubmed
    ..These data combine with recent works to further our understanding of the breadth and impact of protein sumoylation in a diverse array of biological processes. ..
  8. Gómez Herreros F, Rodríguez Galán O, Morillo Huesca M, Maya D, Arista Romero M, de la Cruz J, et al. Balanced production of ribosome components is required for proper G1/S transition in Saccharomyces cerevisiae. J Biol Chem. 2013;288:31689-700 pubmed publisher
    ..This regulatory pathway resembles the p53-dependent nucleolar-stress checkpoint response described in human cells, which indicates that this is a general control strategy extended throughout eukaryotes. ..
  9. Schäfer T, Maco B, Petfalski E, Tollervey D, Bottcher B, Aebi U, et al. Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Nature. 2006;441:651-5 pubmed
    ..In vivo depletion of Hrr25 inhibits growth and leads to the accumulation of immature 40S subunits that contain unstably bound Rps3. We conclude that the kinase activity of Hrr25 regulates the maturation of 40S ribosomal subunits. ..

More Information

Publications10

  1. Dieci G, Ruotolo R, Braglia P, Carles C, Carpentieri A, Amoresano A, et al. Positive modulation of RNA polymerase III transcription by ribosomal proteins. Biochem Biophys Res Commun. 2009;379:489-93 pubmed publisher