Gene Symbol: RPL22A
Description: ribosomal 60S subunit protein L22A
Alias: ribosomal 60S subunit protein L22A
Species: Saccharomyces cerevisiae S288c
Greber B, Gerhardy S, Leitner A, Leibundgut M, Salem M, Boehringer D, et al
. Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation. Cell. 2016;164:91-102 pubmed publisher
..We provide genetic and biochemical evidence that failure to insert the C terminus of Rei1 precludes subsequent steps of 60S maturation. ..
Otaka E, Higo K, Osawa S. Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast. Biochemistry. 1982;21:4545-50 pubmed
..T., Möller, W., Amons, R., & Yaguchi, M. (1980) in Ribosomes: Structure, Function and Genetics (Chambliss, G., et al., Eds.) pp 297-332, University Park Press, Baltimore, MD; M. Yaguchi, unpublished experiments]. ..
Gabunilas J, Chanfreau G. Splicing-Mediated Autoregulation Modulates Rpl22p Expression in Saccharomyces cerevisiae. PLoS Genet. 2016;12:e1005999 pubmed publisher
..These results demonstrate an autoregulatory mechanism that fine-tunes the expression of the Rpl22 protein and by extension Rpl22p paralog composition according to the cellular demands for ribosome biogenesis. ..
Kim S, Strich R. Rpl22 is required for IME1 mRNA translation and meiotic induction in S. cerevisiae. Cell Div. 2016;11:10 pubmed publisher
..This study demonstrates that IME1 mRNA translation requires Rpl22A and Rpl22B, eukaryotic-specific ribosomal protein paralogs of the 60S large subunit...
Matecic M, Stuart S, Holmes S. SIR2-induced inviability is suppressed by histone H4 overexpression. Genetics. 2002;162:973-6 pubmed
..These results suggest a direct and specific interaction between Sir2 and H4 in the silencing mechanism. ..
Greber B, Boehringer D, Montellese C, Ban N. Cryo-EM structures of Arx1 and maturation factors Rei1 and Jjj1 bound to the 60S ribosomal subunit. Nat Struct Mol Biol. 2012;19:1228-33 pubmed publisher