Gene Symbol: REB1
Description: DNA-binding protein REB1
Alias: GRF2, DNA-binding protein REB1
Species: Saccharomyces cerevisiae S288c
Fath S, Milkereit P, Podtelejnikov A, Bischler N, Schultz P, Bier M, et al
. Association of yeast RNA polymerase I with a nucleolar substructure active in rRNA synthesis and processing. J Cell Biol. 2000;149:575-90 pubmed
..Our results support the idea that a functional nucleolar subdomain formed independently of the state of rDNA transcription may serve as a scaffold for coordinated rRNA synthesis and processing. ..
McCullagh E, Seshan A, El Samad H, Madhani H. Coordinate control of gene expression noise and interchromosomal interactions in a MAP kinase pathway. Nat Cell Biol. 2010;12:954-62 pubmed publisher
..Consequently, cells may have evolved mechanisms to suppress noise by controlling these interactions. ..
Lin L, Chamberlain L, Zhu L, Green M. Analysis of Gal4-directed transcription activation using Tra1 mutants selectively defective for interaction with Gal4. Proc Natl Acad Sci U S A. 2012;109:1997-2002 pubmed publisher
..Finally, we show that although Tra1 is targeted by other activators, these interactions are unaffected by GID mutations, revealing an unanticipated specificity of the Gal4-Tra1 interaction. ..
Wang Q, Donze D. Transcription factor Reb1 is required for proper transcriptional start site usage at the divergently transcribed TFC6-ESC2 locus in Saccharomyces cerevisiae. Gene. 2016;594:108-116 pubmed publisher
..cerevisiae, these regions are adjacent to binding sites for general regulatory transcription factors, and the Reb1 protein is commonly bound to promoter DNA near such regions...
Matveenko A, Belousov M, Bondarev S, Moskalenko S, Zhouravleva G. [Identification of new genes that affect [PSI^(+)] prion toxicity in Saccharomyces cerevisiae yeast]. Mol Biol (Mosk). 2016;50:803-813 pubmed
..It was found that ABF1, FKH2, and REB1 overexpression decreased the growth of strains in a prion-dependent manner and, thus, might influence [PSI^(+)] ..
Koerber R, Rhee H, Jiang C, Pugh B. Interaction of transcriptional regulators with specific nucleosomes across the Saccharomyces genome. Mol Cell. 2009;35:889-902 pubmed publisher
..including those that (1) bind histones (Bdf1/SWR1 and Srm1), (2) bind specific DNA sequences (Rap1 and Reb1), and (3) potentially collide with nucleosomes during transcription (RNA polymerase II)...
Mayan M. RNAP-II transcribes two small RNAs at the promoter and terminator regions of the RNAP-I gene in Saccharomyces cerevisiae. Yeast. 2013;30:25-32 pubmed publisher
..This report suggests that cryptic transcription by RNAP-II may be required for normal transcription by RNAP-I in the ribosomal locus of S. cerevisiae. ..
Kamei Y, Tai A, Dakeyama S, Yamamoto K, Inoue Y, Kishimoto Y, et al
. Transcription factor genes essential for cell proliferation and replicative lifespan in budding yeast. Biochem Biophys Res Commun. 2015;463:351-6 pubmed publisher
..Heterozygous diploid knockout strains for FHL1, RAP1, REB1, and MCM1 genes showed significantly short lifespan...
Jeong S, Lang W, Reeder R. The release element of the yeast polymerase I transcription terminator can function independently of Reb1p. Mol Cell Biol. 1995;15:5929-36 pubmed
..We discuss possible mechanisms whereby this polI release element might function. ..