PYC1

Summary

Gene Symbol: PYC1
Description: pyruvate carboxylase 1
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. ncbi Yeast pyruvate carboxylase: identification of two genes encoding isoenzymes
    M E Walker
    Department of Biochemistry, University of Adelaide, South Australia
    Biochem Biophys Res Commun 176:1210-7. 1991
  2. ncbi Localization and kinetics of pyruvate-metabolizing enzymes in relation to aerobic alcoholic fermentation in Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621
    H van Urk
    Department of Microbiology and Enzymology, Delft University of Technology, The Netherlands
    Biochim Biophys Acta 992:78-86. 1989
  3. ncbi Regulation of pyruvate carboxylase isozyme (PYC1, PYC2) gene expression in Saccharomyces cerevisiae during fermentative and nonfermentative growth
    N K Brewster
    Department of Biochemistry, University of Adelaide, Australia
    Arch Biochem Biophys 311:62-71. 1994
  4. ncbi A mutation affecting carbon catabolite repression suppresses growth defects in pyruvate carboxylase mutants from Saccharomyces cerevisiae
    M A Blazquez
    Instituto de Investigaciones Biomédicas del C S I C, Unidad de Bioquímica y Genética de Levaduras, Madrid, Spain
    FEBS Lett 377:197-200. 1995
  5. ncbi Conserved Glu40 and Glu433 of the biotin carboxylase domain of yeast pyruvate carboxylase I isoenzyme are essential for the association of tetramers
    Sarawut Jitrapakdee
    Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    Int J Biochem Cell Biol 39:2120-34. 2007
  6. ncbi Location of three key enzymes of gluconeogenesis in baker's yeast
    S Haarasilta
    Arch Microbiol 113:159-61. 1977

Detail Information

Publications7

  1. ncbi Yeast pyruvate carboxylase: identification of two genes encoding isoenzymes
    M E Walker
    Department of Biochemistry, University of Adelaide, South Australia
    Biochem Biophys Res Commun 176:1210-7. 1991
    ..We have mapped the genes encoding both enzymes and shown the previously characterised gene, designated PYC1, to be on chromosome VII whilst PYC2 is on chromosome II.
  2. ncbi Localization and kinetics of pyruvate-metabolizing enzymes in relation to aerobic alcoholic fermentation in Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621
    H van Urk
    Department of Microbiology and Enzymology, Delft University of Technology, The Netherlands
    Biochim Biophys Acta 992:78-86. 1989
    ..Rather, a high glycolytic flux and a high level of this enzyme are decisive for the occurrence of alcoholic fermentation after transfer of cells from glucose limitation to glucose excess...
  3. ncbi Regulation of pyruvate carboxylase isozyme (PYC1, PYC2) gene expression in Saccharomyces cerevisiae during fermentative and nonfermentative growth
    N K Brewster
    Department of Biochemistry, University of Adelaide, Australia
    Arch Biochem Biophys 311:62-71. 1994
    ..cerevisiae there are two isoenzymes of pyruvate carboxylase (Pyc) encoded by separate genes, designated PYC1 and PYC2...
  4. ncbi A mutation affecting carbon catabolite repression suppresses growth defects in pyruvate carboxylase mutants from Saccharomyces cerevisiae
    M A Blazquez
    Instituto de Investigaciones Biomédicas del C S I C, Unidad de Bioquímica y Genética de Levaduras, Madrid, Spain
    FEBS Lett 377:197-200. 1995
    Yeasts with disruptions in the genes PYC1 and PYC2 encoding the isoenzymes of pyruvate carboxylase cannot grow in a glucose-ammonium medium (Stucka et al. (1991) Mol. Gen. Genet. 229, 307-315)...
  5. ncbi Conserved Glu40 and Glu433 of the biotin carboxylase domain of yeast pyruvate carboxylase I isoenzyme are essential for the association of tetramers
    Sarawut Jitrapakdee
    Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    Int J Biochem Cell Biol 39:2120-34. 2007
    ..To identify this domain we co-expressed yeast pyruvate carboxylase 1 isozyme (Pyc1) with an N-terminal myc tag, together with constructs encoding either the biotin carboxylase (BC) domain or the ..
  6. ncbi Location of three key enzymes of gluconeogenesis in baker's yeast
    S Haarasilta
    Arch Microbiol 113:159-61. 1977
    ..On the evidence obtained from zonal separations these three enzymes of gluconeogenesis are most probably located in the soluble cytosol...