Gene Symbol: PMT5
Description: putative dolichyl-phosphate-mannose-protein mannosyltransferase PMT5
Species: Saccharomyces cerevisiae S288c
Boskovic J, Soler Mira A, Garcia Cantalejo J, Ballesta J, Jimenez A, Remacha M. The sequence of a 16,691 bp segment of Saccharomyces cerevisiae chromosome IV identifies the DUN1, PMT1, PMT5, SRP14 and DPR1 genes, and five new open reading frames. Yeast. 1996;12:1377-84 pubmed
..five of these were previously identified as genes DUN1, PMT1, PMT5, SRP14 and DPR1...
Jain S, Stanford N, Bhagwat N, Seiler B, Costanzo M, Boone C, et al
. Identification of a novel lysophospholipid acyltransferase in Saccharomyces cerevisiae. J Biol Chem. 2007;282:30562-9 pubmed
..Therefore, Lpt1p, a member of the membrane-bound o-acyltransferase gene family, seems to work in conjunction with Slc1 to mediate the incorporation of unsaturated acyl chains into the sn-2 position of phospholipids. ..
Gentzsch M, Tanner W. The PMT gene family: protein O-glycosylation in Saccharomyces cerevisiae is vital. EMBO J. 1996;15:5752-9 pubmed
..The results show that protein O-glycosylation is essential for cell wall rigidity and cell integrity and that this protein modification, therefore, is vital for Saccharomyces cerevisiae. ..
Girrbach V, Strahl S. Members of the evolutionarily conserved PMT family of protein O-mannosyltransferases form distinct protein complexes among themselves. J Biol Chem. 2003;278:12554-62 pubmed
..Our data suggest that protein-protein interactions between the PMT family members offer a point of attack to shut down overall protein O-mannosylation in fungi. ..