Gene Symbol: PHO86
Species: Saccharomyces cerevisiae S288c
Lau W, Howson R, Malkus P, Schekman R, O Shea E. Pho86p, an endoplasmic reticulum (ER) resident protein in Saccharomyces cerevisiae, is required for ER exit of the high-affinity phosphate transporter Pho84p. Proc Natl Acad Sci U S A. 2000;97:1107-12 pubmed
..is localized to the endoplasmic reticulum (ER) and fails to be targeted to the plasma membrane in the absence of Pho86p. Utilizing an in vitro vesicle budding assay, we demonstrate that Pho86p is required for packaging of Pho84p into ..
Almaguer C, Mantella D, Perez E, Patton Vogt J. Inositol and phosphate regulate GIT1 transcription and glycerophosphoinositol incorporation in Saccharomyces cerevisiae. Eukaryot Cell. 2003;2:729-36 pubmed
..A genetic screen identified Pho86p, which is required for targeting of the major phosphate transporter (Pho84p) to the plasma membrane, as affecting ..
Bun Ya M, Shikata K, Nakade S, Yompakdee C, Harashima S, Oshima Y. Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae. Curr Genet. 1996;29:344-51 pubmed
..These and the other findings suggest that the Pho86p and Pho87p proteins collaborate with Pho84p in Pi uptake.
Yompakdee C, Bun Ya M, Shikata K, Ogawa N, Harashima S, Oshima Y. A putative new membrane protein, Pho86p, in the inorganic phosphate uptake system of Saccharomyces cerevisiae. Gene. 1996;171:41-7 pubmed
..Western blotting analysis of cell extracts revealed that Pho86p, tagged with c-Myc, was fractionated into a water-insoluble fraction...
Yompakdee C, Ogawa N, Harashima S, Oshima Y. A putative membrane protein, Pho88p, involved in inorganic phosphate transport in Saccharomyces cerevisiae. Mol Gen Genet. 1996;251:580-90 pubmed
..and the results of an analysis of its cellular localization suggested that Pho88p is a membrane protein similar to Pho86p. Both disruption and high dosage of PHO88 or PHO86 resulted in reduced Pi uptake...
Kota J, Ljungdahl P. Specialized membrane-localized chaperones prevent aggregation of polytopic proteins in the ER. J Cell Biol. 2005;168:79-88 pubmed
..Also, we show that the integral ER proteins, Gsf2p, Pho86p, and Chs7p, function similarly to Shr3p...