Gene Symbol: PGM1
Description: phosphoglucomutase PGM1
Alias: phosphoglucomutase PGM1
Species: Saccharomyces cerevisiae S288c
Howard S, Deminoff S, Herman P. Increased phosphoglucomutase activity suppresses the galactose growth defect associated with elevated levels of Ras signaling in S. cerevisiae. Curr Genet. 2006;49:1-6 pubmed
..This screen identified two genes, PGM1 and PCM1, that encode proteins with phosphoglucomutase activity...
Marchase R, Bounelis P, Brumley L, Dey N, Browne B, Auger D, et al
. Phosphoglucomutase in Saccharomyces cerevisiae is a cytoplasmic glycoprotein and the acceptor for a Glc-phosphotransferase. J Biol Chem. 1993;268:8341-9 pubmed
..When phosphoglucomutase was overexpressed, an increase was seen in Glc-phosphotransferase acceptor activity and in specific metabolic labeling of the acceptor by glucose and mannose. ..
Hirata Y, Andoh T, Asahara T, Kikuchi A. Yeast glycogen synthase kinase-3 activates Msn2p-dependent transcription of stress responsive genes. Mol Biol Cell. 2003;14:302-12 pubmed
..Because neither Msn2p-GSK-3 complex formation nor GSK-3-dependent phosphorylation of Msn2p could be detected, the regulation of Msn2p by GSK-3 may be indirect. ..
Gao L, Bretscher A. Analysis of unregulated formin activity reveals how yeast can balance F-actin assembly between different microfilament-based organizations. Mol Biol Cell. 2008;19:1474-84 pubmed publisher
..Thus, cells must have a way of ensuring a proper balance between actin assembly pathways. ..
Boles E, Liebetrau W, Hofmann M, Zimmermann F. A family of hexosephosphate mutases in Saccharomyces cerevisiae. Eur J Biochem. 1994;220:83-96 pubmed
The Saccharomyces cerevisiae PGM1 and PGM2 genes encoding two phosphoglucomutase isoenzymes have been isolated and sequenced...
Daran J, Bell W, Francois J. Physiological and morphological effects of genetic alterations leading to a reduced synthesis of UDP-glucose in Saccharomyces cerevisiae. FEMS Microbiol Lett. 1997;153:89-96 pubmed
Rutter J, Probst B, McKnight S. Coordinate regulation of sugar flux and translation by PAS kinase. Cell. 2002;111:17-28 pubmed
..These studies provide evidence of a cell-autonomous signaling system that both controls and connects the balance of fuel consumption/storage to protein synthesis. ..
Chen Y, Tye B. The yeast Mcm1 protein is regulated posttranscriptionally by the flux of glycolysis. Mol Cell Biol. 1995;15:4631-9 pubmed
..Two of the suppressors, pgm1-1 and pgm1-2, are mutant alleles of PGM1 which encodes a glycolytic enzyme, phosphoglycerate mutase...