PET10

Summary

Gene Symbol: PET10
Description: Pet10p
Alias: Pet10p
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Athenstaedt K, Zweytick D, Jandrositz A, Kohlwein S, Daum G. Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol. 1999;181:6441-8 pubmed
    ..Strains with YBR177c, YMR313c, and YKL140w deleted exhibited phospholipid and/or neutral lipid patterns that were different from the wild-type strain and thus may be further candidate ORFs involved in yeast lipid metabolism. ..
  2. Brown M, Grundy W, Lin D, Cristianini N, Sugnet C, Furey T, et al. Knowledge-based analysis of microarray gene expression data by using support vector machines. Proc Natl Acad Sci U S A. 2000;97:262-7 pubmed
    ..Finally, we use SVMs to predict functional roles for uncharacterized yeast ORFs based on their expression data. ..
  3. Moldavski O, Amen T, Levin Zaidman S, Eisenstein M, Rogachev I, Brandis A, et al. Lipid Droplets Are Essential for Efficient Clearance of Cytosolic Inclusion Bodies. Dev Cell. 2015;33:603-10 pubmed publisher
    ..We further demonstrate a mechanism for IB clearance via a sterol-based metabolite emanating from LDs. Our findings therefore uncover a function for Iml2 and LDs in regulating a critical stage of cellular proteostasis. ..
  4. Gao Q, Binns D, Kinch L, Grishin N, Ortiz N, Chen X, et al. Pet10p is a yeast perilipin that stabilizes lipid droplets and promotes their assembly. J Cell Biol. 2017;216:3199-3217 pubmed publisher
    b>Pet10p is a yeast lipid droplet protein of unknown function. We show that it binds specifically to and is stabilized by droplets containing triacylglycerol (TG)...