Gene Symbol: OSM1
Description: fumarate reductase
Alias: fumarate reductase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Arikawa Y, Enomoto K, Muratsubaki H, Okazaki M. Soluble fumarate reductase isoenzymes from Saccharomyces cerevisiae are required for anaerobic growth. FEMS Microbiol Lett. 1998;165:111-6 pubmed
    In Saccharomyces cerevisiae, the cytosolic and promitochondrial isoenzymes of fumarate reductase are encoded by the FRDS and OSM1 genes, respectively. The product of the OSM1 gene is reported to be required for growth in hypertonic medium...
  2. Camarasa C, Faucet V, Dequin S. Role in anaerobiosis of the isoenzymes for Saccharomyces cerevisiae fumarate reductase encoded by OSM1 and FRDS1. Yeast. 2007;24:391-401 pubmed
    Saccharomyces cerevisiae possesses both a cytoplasmic and a mitochondrial fumarate reductase, encoded by FRDS1 and OSM1, respectively...
  3. Williams C, Jan C, Weissman J. Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014;346:748-51 pubmed publisher
    ..A prominent exception was the fumarate reductase Osm1, known to reside in mitochondria...
  4. Neal S, Dabir D, Wijaya J, Boon C, Koehler C. Osm1 facilitates the transfer of electrons from Erv1 to fumarate in the redox-regulated import pathway in the mitochondrial intermembrane space. Mol Biol Cell. 2017;28:2773-2785 pubmed publisher
    ..Here we show that the fumarate reductase Osm1, which facilitates electron transfer from fumarate to succinate, fills this gap as a new electron ..
  5. Muratsubaki H, Enomoto K. One of the fumarate reductase isoenzymes from Saccharomyces cerevisiae is encoded by the OSM1 gene. Arch Biochem Biophys. 1998;352:175-81 pubmed
    Soluble fumarate reductase from yeast irreversibly catalyzes the reduction of fumarate to succinate and has noncovalently bound flavin adenine dinucleotide...
  6. Enomoto K, Arikawa Y, Muratsubaki H. Physiological role of soluble fumarate reductase in redox balancing during anaerobiosis in Saccharomyces cerevisiae. FEMS Microbiol Lett. 2002;215:103-8 pubmed
    In Saccharomyces cerevisiae, there are two isoenzymes of fumarate reductase (FRDS1 and FRDS2), encoded by the FRDS and OSM1 genes, respectively...