Gene Symbol: OM14
Species: Saccharomyces cerevisiae S288c
Burri L, Vascotto K, Gentle I, Chan N, Beilharz T, Stapleton D, et al
. Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae. FEBS J. 2006;273:1507-15 pubmed
..We purified the novel outer membrane protein Om14 and show it is encoded in the gene YBR230c...
Lauffer S, Mäbert K, Czupalla C, Pursche T, Hoflack B, Rödel G, et al
. Saccharomyces cerevisiae porin pore forms complexes with mitochondrial outer membrane proteins Om14p and Om45p. J Biol Chem. 2012;287:17447-58 pubmed publisher
..Native (BN)-PAGE analysis, co-immunoprecipitation, and tandem affinity purification that the two mt OM proteins Om14p and Om45p associate with the porin pore. Porin molecules seem to assemble independently to build the core unit...
Becker T, Wenz L, Krüger V, Lehmann W, Müller J, Goroncy L, et al
. The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins. J Cell Biol. 2011;194:387-95 pubmed publisher
..We conclude that the Mim1 complex plays a central role in the import of ?-helical outer membrane proteins with multiple transmembrane segments. ..
Wenz L, Opaliński L, Schuler M, Ellenrieder L, Ieva R, Böttinger L, et al
. The presequence pathway is involved in protein sorting to the mitochondrial outer membrane. EMBO Rep. 2014;15:678-85 pubmed publisher
..Assembly of Om45 in the outer membrane involves the MIM machinery. Om45 thus follows a new mitochondrial biogenesis pathway that uses elements of the presequence import pathway to direct a protein to the outer membrane. ..
Lesnik C, Cohen Y, Atir Lande A, Schuldiner M, Arava Y. OM14 is a mitochondrial receptor for cytosolic ribosomes that supports co-translational import into mitochondria. Nat Commun. 2014;5:5711 pubmed publisher
..Here, we identify the Saccharomyces cerevisiae outer membrane protein OM14 as a receptor for NAC...