OCA6

Summary

Gene Symbol: OCA6
Description: protein-tyrosine-phosphatase
Alias: protein-tyrosine-phosphatase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Romá Mateo C, Sacristán Reviriego A, Beresford N, Caparrós Martín J, Culiáñez Macià F, Martín H, et al. Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms. Mol Genet Genomics. 2011;285:341-54 pubmed publisher
    Dual-specificity phosphatases (DSPs) constitute a large protein tyrosine phosphatase (PTP) family, with examples in distant evolutive phyla...
  2. Armakola M, Higgins M, Figley M, Barmada S, Scarborough E, Diaz Z, et al. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nat Genet. 2012;44:1302-9 pubmed publisher
    ..Our findings provide insight into TDP-43-mediated cytotoxicity and suggest that decreasing Dbr1 activity could be a potential therapeutic approach for ALS. ..