Gene Symbol: NTR2
Species: Saccharomyces cerevisiae S288c
Tsai R, Fu R, Yeh F, Tseng C, Lin Y, Huang Y, et al
. Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2. Genes Dev. 2005;19:2991-3003 pubmed
Two novel yeast splicing factors required for spliceosome disassembly have been identified. Ntr1 and Ntr2 (NineTeen complex-Related proteins) were identified for their weak association with components of the Prp19-associated complex...
Boon K, Auchynnikava T, Edwalds Gilbert G, Barrass J, Droop A, Dez C, et al
. Yeast ntr1/spp382 mediates prp43 function in postspliceosomes. Mol Cell Biol. 2006;26:6016-23 pubmed
The Ntr1 and Ntr2 proteins of Saccharomyces cerevisiae have been reported to interact with proteins involved in pre-mRNA splicing, but their roles in the splicing process are unknown...
Tsai R, Tseng C, Lee P, Chen H, Fu R, Chang K, et al
. Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly. Mol Cell Biol. 2007;27:8027-37 pubmed
The Saccharomyces cerevisiae splicing factors Ntr1 (also known as Spp382) and Ntr2 form a stable complex and can further associate with DExD/H-box RNA helicase Prp43 to form a functional complex, termed the NTR complex, which catalyzes ..
Fourmann J, Tauchert M, Ficner R, Fabrizio P, Luhrmann R. Regulation of Prp43-mediated disassembly of spliceosomes by its cofactors Ntr1 and Ntr2. Nucleic Acids Res. 2017;45:4068-4080 pubmed publisher
The DEAH-box NTPase Prp43 disassembles spliceosomes in co-operation with the cofactors Ntr1/Spp382 and Ntr2, forming the NTR complex...
Pandit S, Paul S, Zhang L, Chen M, Durbin N, Harrison S, et al
. Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function. Genetics. 2009;183:195-206 pubmed publisher
..These and related data establish the value of this dosage interference assay for finding genes that alter cellular splicing and define Sqs1p and Cwc23p as prospective modulators of Spp382p-stimuated Prp43p function. ..
Chen H, Tseng C, Tsai R, Chung C, Cheng S. Link of NTR-mediated spliceosome disassembly with DEAH-box ATPases Prp2, Prp16, and Prp22. Mol Cell Biol. 2013;33:514-25 pubmed publisher
..Prp43 associates with Ntr1 and Ntr2 to form the NTR complex and is recruited to the spliceosome via the interaction of Ntr2 and U5 component Brr2...