Gene Symbol: MRS2
Species: Saccharomyces cerevisiae S288c
- Khan M, Sjöblom B, Schweyen R, Djinovic Carugo K. Crystallization and preliminary X-ray diffraction analysis of the N-terminal domain of Mrs2, a magnesium ion transporter from yeast inner mitochondrial membrane. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010;66:658-61 pubmed publisherb>Mrs2 transporters are distantly related to the major bacterial Mg(2+) transporter CorA and to Alr1, which is found in the plasma membranes of lower eukaryotes...
- Khan M, Sponder G, Sjöblom B, Svidova S, Schweyen R, Carugo O, et al. Structural and functional characterization of the N-terminal domain of the yeast Mg2+ channel Mrs2. Acta Crystallogr D Biol Crystallogr. 2013;69:1653-64 pubmed publisherMg(2+) translocation across cellular membranes is crucial for a myriad of physiological processes. Eukaryotic Mrs2 transporters are distantly related to the major bacterial Mg(2+) transporter CorA, the structure of which displays a bundle ..
- Cui Y, Zhao S, Wang J, Wang X, Gao B, Fan Q, et al. A novel mitochondrial carrier protein Mme1 acts as a yeast mitochondrial magnesium exporter. Biochim Biophys Acta. 2015;1853:724-32 pubmed publisher..Previously, two mitochondrial Mg2+ importers, Mrs2 and Lpe10, were characterized for mitochondrial Mg2+ uptake...
- Van Dyck E, Jank B, Ragnini A, Schweyen R, Duyckaerts C, Sluse F, et al. Overexpression of a novel member of the mitochondrial carrier family rescues defects in both DNA and RNA metabolism in yeast mitochondria. Mol Gen Genet. 1995;246:426-36 pubmedThe PIF1 and MRS2 gene products have previously been shown to be essential for mitochondrial DNA maintenance at elevated temperatures and mitochondrial group II intron splicing, respectively, in the yeast Saccharomyces cerevisiae...