MRPL40

Summary

Gene Symbol: MRPL40
Description: mitochondrial 54S ribosomal protein YmL40
Alias: mitochondrial 54S ribosomal protein YmL40
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Kitakawa M, Graack H, Grohmann L, Goldschmidt Reisin S, Herfurth E, Wittmann Liebold B, et al. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Eur J Biochem. 1997;245:449-56 pubmed
    ..Furthermore, we determined the N-terminal amino acid sequences of seven small subunit proteins and subsequently identified the genes for five of them, three of which were found to be new. ..
  2. Jia L, Kaur J, Stuart R. Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly. Eukaryot Cell. 2009;8:1792-802 pubmed publisher
    ..interface, and we demonstrate here a close association of Oxa1 and the large ribosomal subunit protein, MrpL40. Evidence to indicate that a close physical and functional relationship exists between MrpL40 and another large ..
  3. Kaur J, Stuart R. Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria. EMBO Rep. 2011;12:950-5 pubmed publisher
    ..Finally, data supporting the idea that the inner mitochondrial membrane acts as a platform for the ribosome assembly process are discussed. ..
  4. De Silva D, Fontanesi F, Barrientos A. The DEAD box protein Mrh4 functions in the assembly of the mitochondrial large ribosomal subunit. Cell Metab. 2013;18:712-25 pubmed publisher
    ..We conclude that Mrh4 plays an essential role during the late stages of mitoribosome assembly by promoting remodeling of the 21S rRNA-protein interactions. ..
  5. Accardi R, Oxelmark E, Jauniaux N, De Pinto V, Marchini A, Tommasino M. High levels of the mitochondrial large ribosomal subunit protein 40 prevent loss of mitochondrial DNA in null mmf1 Saccharomyces cerevisiae cells. Yeast. 2004;21:539-48 pubmed
    ..Using a multicopy suppression approach, we have identified a protein of the mitochondrial large ribosomal subunit, MRPL40, which stabilizes mtDNA in Deltammf1 cells...
  6. Daoud R, Forget L, Lang B. Yeast mitochondrial RNase P, RNase Z and the RNA degradosome are part of a stable supercomplex. Nucleic Acids Res. 2012;40:1728-36 pubmed publisher
    ..Finally, the question of mt-RNase P localization within mitochondria was investigated, by GFP-tracing of a known protein subunit (Rpm2p). We find that about equal fractions of RNase P are soluble versus membrane-attached. ..
  7. Gruschke S, Gröne K, Heublein M, Hölz S, Israel L, Imhof A, et al. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J Biol Chem. 2010;285:19022-8 pubmed publisher
    ..This unique architecture of the tunnel exit is presumably an adaptation of the translation system to the specific requirements of the organelle. ..