Gene Symbol: MRK1
Description: putative serine/threonine protein kinase MRK1
Species: Saccharomyces cerevisiae S288c
Kassir Y, Rubin Bejerano I, Mandel Gutfreund Y. The Saccharomyces cerevisiae GSK-3 beta homologs. Curr Drug Targets. 2006;7:1455-65 pubmed
Yeast cells carry four homologs of GSK-3beta, RIM11, MCK1, MRK1 and YGK3. The significant homologs are RIM11 and MCK1 that presumably arose from a recent genome duplication followed by a rapid divergence...
Zhou J, Zhong Q, Li G, Greenberg M. Loss of cardiolipin leads to longevity defects that are alleviated by alterations in stress response signaling. J Biol Chem. 2009;284:18106-14 pubmed publisher
..These findings show for the first time that perturbation of CL synthesis leads to decreased longevity in yeast, which is restored by altering signaling through stress response pathways. ..
Andoh T, Hirata Y, Kikuchi A. Yeast glycogen synthase kinase 3 is involved in protein degradation in cooperation with Bul1, Bul2, and Rsp5. Mol Cell Biol. 2000;20:6712-20 pubmed
The yeast Saccharomyces cerevisiae has four genes, MCK1, MDS1 (RIM11), MRK1, and YOL128c, that encode glycogen synthase kinase 3 (GSK-3) homologs...
Hirata Y, Andoh T, Asahara T, Kikuchi A. Yeast glycogen synthase kinase-3 activates Msn2p-dependent transcription of stress responsive genes. Mol Biol Cell. 2003;14:302-12 pubmed
The yeast Saccharomyces cerevisiae has four genes, MCK1, MDS1 (RIM11), MRK1, and YOL128c, that encode homologues of mammalian glycogen synthase kinase 3 (GSK-3)...
Yabuki Y, Kodama Y, Katayama M, Sakamoto A, Kanemaru H, Wan K, et al
. Glycogen synthase kinase-3 is involved in regulation of ribosome biogenesis in yeast. Biosci Biotechnol Biochem. 2014;78:800-5 pubmed publisher
..Here, we found that Rrs1 interacts with two homologs of the glycogen synthase kinase-3 (GSK-3), Rim11, and Mrk1. Rrs1 possesses a repetitive consensus amino acid sequence for phosphorylation by GSK-3, and mutation of this ..