Gene Symbol: MIC19
Alias: AIM13, MCS19, Mic19p
Species: Saccharomyces cerevisiae S288c
Harner M, Korner C, Walther D, Mokranjac D, Kaesmacher J, Welsch U, et al
. The mitochondrial contact site complex, a determinant of mitochondrial architecture. EMBO J. 2011;30:4356-70 pubmed publisher
..Loss of MICOS subunits results in loss of respiratory competence and altered inheritance of mitochondrial DNA. ..
Zerbes R, Bohnert M, Stroud D, von der Malsburg K, Kram A, Oeljeklaus S, et al
. Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains. J Mol Biol. 2012;422:183-91 pubmed publisher
Bohnert M, Wenz L, Zerbes R, Horvath S, Stroud D, von der Malsburg K, et al
. Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane. Mol Biol Cell. 2012;23:3948-56 pubmed publisher
..We conclude that MINOS interacts with TOM and SAM independently and that the core subunit mitofilin is involved in biogenesis of outer membrane ?-barrel proteins. ..
Harner M, Unger A, Izawa T, Walther D, Ozbalci C, Geimer S, et al
. Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture. elife. 2014;3:e01684 pubmed publisher
..In conclusion, Aim24 by interacting with the MICOS complex plays a key role in mitochondrial architecture, composition and function. DOI: http://dx.doi.org/10.7554/eLife.01684.001. ..
Chojnacka M, Gornicka A, Oeljeklaus S, Warscheid B, Chacinska A. Cox17 Protein Is an Auxiliary Factor Involved in the Control of the Mitochondrial Contact Site and Cristae Organizing System. J Biol Chem. 2015;290:15304-12 pubmed publisher
..However, the Cox17-MICOS interaction is regulated by copper ions. We propose that Cox17 is a newly identified factor involved in maintaining the architecture of the MICOS complex. ..
Sakowska P, Jans D, Mohanraj K, Riedel D, Jakobs S, Chacinska A. The Oxidation Status of Mic19 Regulates MICOS Assembly. Mol Cell Biol. 2015;35:4222-37 pubmed publisher
..However, the mechanisms that underlie MICOS regulation remain poorly understood. MIC19, a peripheral protein of the inner membrane and component of the MICOS complex, was previously reported to be ..