Gene Symbol: MDM31
Species: Saccharomyces cerevisiae S288c
Dimmer K, Jakobs S, Vogel F, Altmann K, Westermann B. Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol. 2005;168:103-15 pubmed
The MDM31 and MDM32 genes are required for normal distribution and morphology of mitochondria in the yeast Saccharomyces cerevisiae...
Dimmer K, Fritz S, Fuchs F, Messerschmitt M, Weinbach N, Neupert W, et al
. Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell. 2002;13:847-53 pubmed
..These data provide a comprehensive picture of the cellular processes and molecular components required for mitochondrial function and structure in a simple eukaryotic cell. ..
Kucejova B, Kucej M, Petrezselyova S, Abelovska L, Tomaska L. A screen for nigericin-resistant yeast mutants revealed genes controlling mitochondrial volume and mitochondrial cation homeostasis. Genetics. 2005;171:517-26 pubmed
..Taken together, these data indicate that Mdm31p and Mdm32p control mitochondrial morphology through regulation of mitochondrial cation homeostasis and the ..
Lee M, Dohlman H. Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor. Curr Biol. 2008;18:211-5 pubmed publisher
..Our data suggest that intracellular proteins function in cooperation with mating pheromones to amplify G protein signaling, thereby leading to full pathway activation. ..
Tamura Y, Onguka O, Hobbs A, Jensen R, Iijima M, Claypool S, et al
. Role for two conserved intermembrane space proteins, Ups1p and Ups2p, [corrected] in intra-mitochondrial phospholipid trafficking. J Biol Chem. 2012;287:15205-18 pubmed publisher
..the role of the conserved intermembrane space proteins, Ups1p and Ups2p, and an inner membrane protein, Mdm31p, in phospholipid metabolism...
Song Q, Johnson C, Wilson T, Kumar A. Pooled segregant sequencing reveals genetic determinants of yeast pseudohyphal growth. PLoS Genet. 2014;10:e1004570 pubmed publisher
..Collectively, this work identifies new determinants of pseudohyphal growth, while highlighting the coevolution of protein complexes and organelle structures within a given genome in specifying complex phenotypes. ..
Miyata N, Goda N, Matsuo K, Hoketsu T, Kuge O. Cooperative function of Fmp30, Mdm31, and Mdm32 in Ups1-independent cardiolipin accumulation in the yeast Saccharomyces cerevisiae. Sci Rep. 2017;7:16447 pubmed publisher
..the Ups1-independent and low-level PE-enhanced CL accumulation was shown to depend on the functions of FMP30, MDM31, and MDM32. In addition, the physical interactions of Fmp30 with Mdm31 and Mdm32 were revealed...