Gene Symbol: MDM1
Description: Mdm1p
Alias: Mdm1p
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. McConnell S, Stewart L, Talin A, Yaffe M. Temperature-sensitive yeast mutants defective in mitochondrial inheritance. J Cell Biol. 1990;111:967-76 pubmed
    ..Two of these mutants contain single, recessive, nuclear mutations, mdm1 and mdm2, that cause temperature-sensitive growth and aberrant mitochondrial distribution at the nonpermissive ..
  2. McConnell S, Yaffe M. Nuclear and mitochondrial inheritance in yeast depends on novel cytoplasmic structures defined by the MDM1 protein. J Cell Biol. 1992;118:385-95 pubmed
    ..The MDM1 gene was cloned by complementation, and its sequence revealed an open reading frame encoding a potential protein ..
  3. Fisk H, Yaffe M. Mutational analysis of Mdm1p function in nuclear and mitochondrial inheritance. J Cell Biol. 1997;138:485-94 pubmed
    Nuclear and mitochondrial transmission to daughter buds of Saccharomyces cerevisiae depends on Mdm1p, an intermediate filament-like protein localized to numerous punctate structures distributed throughout the yeast cell cytoplasm...
  4. Henne W, Zhu L, Balogi Z, Stefan C, Pleiss J, Emr S. Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein. J Cell Biol. 2015;210:541-51 pubmed publisher
    ..Screening implicated Phox (PX) domain-containing protein Mdm1 in endomembrane dynamics...
  5. Hermann G, Shaw J. Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol. 1998;14:265-303 pubmed
  6. Chasse S, Flanary P, Parnell S, Hao N, Cha J, Siderovski D, et al. Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae. Eukaryot Cell. 2006;5:330-46 pubmed
    ..In the yeast Saccharomyces cerevisiae there are four RGS-homologous proteins (Sst2, Rgs2, Rax1, and Mdm1) and two Galpha proteins (Gpa1 and Gpa2)...
  7. Yu J, Lemmon M. All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate. J Biol Chem. 2001;276:44179-84 pubmed
    ..Our results establish that PtdIns-3-P, and not other phosphoinositides, is the target of all PX domains in S. cerevisiae and suggest a role for PX domains in assembly of multiprotein complexes at specific membrane surfaces. ..
  8. Fisk H, Yaffe M. A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae. J Cell Biol. 1999;145:1199-208 pubmed
    The smm1 mutation suppresses defects in mitochondrial distribution and morphology caused by the mdm1-252 mutation in the yeast Saccharomyces cerevisiae...